Salmonella "RecAmends" self-healing
- PMID: 34883061
- DOI: 10.1016/j.chom.2021.11.009
Salmonella "RecAmends" self-healing
Abstract
Persistent bacteria contribute to antibiotic treatment failure, potentially fueling resistance. Persisters must survive host defenses while retaining infective capacity after antibiotic cessation. In this issue of Cell Host and Microbe, Hill et al. identify bacterial RecA as a DNA repair factor that allows intracellular bacteria survival, regrowth, and relapse.
Copyright © 2021 Elsevier Inc. All rights reserved.
Comment on
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The vulnerable versatility of Salmonella antibiotic persisters during infection.Cell Host Microbe. 2021 Dec 8;29(12):1757-1773.e10. doi: 10.1016/j.chom.2021.10.002. Epub 2021 Nov 2. Cell Host Microbe. 2021. PMID: 34731646
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