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Review
. 2022 Apr-May;24(3):104925.
doi: 10.1016/j.micinf.2021.104925. Epub 2021 Dec 6.

Porphyromonas gingivalis in oral squamous cell carcinoma: a review

Suchitra Singh  1 , Ajay Kumar Singh  2
Affiliations
Free article
Review

Porphyromonas gingivalis in oral squamous cell carcinoma: a review

Suchitra Singh et al. Microbes Infect. 2022 Apr-May.
Free article

Abstract

Oral cancer contributes significantly to the global cancer burden. Oral bacteria play an important role in the spread of oral cancer, according to mounting evidence. The most proven instance is the carcinogenic implications of Porphyromonas gingivalis, a key pathogen in chronic periodontitis. It is imperative to understand the pathogenesis of P. gingivalis in OSCC. This review aims to gather and assess scientific shreds of evidence on the involvement of P. gingivalis in the molecular mechanism of oral squamous cell carcinoma.

Keywords: Metastasis; Oral squamous cell carcinoma (OSCC); Periodontitis; Porphyromonas gingivalis; Virulence factors.

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Conflict of interest statement

Declaration of competing interest The Author(s) declares there is no conflict of interest among authors to publish this article.

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