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. 1986 Jul;39(7):713-6.
doi: 10.1136/jcp.39.7.713.

Autoimmunity in chronic lymphocytic leukaemia

T J Hamblin, D G Oscier, B J Young

Autoimmunity in chronic lymphocytic leukaemia

T J Hamblin et al. J Clin Pathol. 1986 Jul.

Abstract

The prevalence of autoantibodies in B cell chronic lymphocytic leukaemia (B-CLL) was investigated. A lower prevalence of autoimmune haemolytic anaemia than that found in other series was found: large numbers of non-progressive stage A disease cases were included, in which the prevalence of autoimmune haemolytic anaemia is low. Non-haematological autoantibodies were no commoner than in age matched controls. Whatever explanation is offered for autoimmune phenomena in B-CLL it must take account of the fact that those phenomena are virtually confined to autoantibodies against the formed elements of the blood.

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