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Editorial
. 2021 Nov 25;22(23):12725.
doi: 10.3390/ijms222312725.

Osteoporosis: From Molecular Mechanisms to Therapies 3.0

Chih-Hsin Tang  1   2   3
Affiliations
Editorial

Osteoporosis: From Molecular Mechanisms to Therapies 3.0

Chih-Hsin Tang. Int J Mol Sci. .

Abstract

Osteoporosis is a common skeletal disorder that occurs as a result of an imbalance between bone resorption and bone formation, with bone breakdown exceeding bone building. Bone resorption inhibitors, e.g., bisphosphonates, have been designed to treat osteoporosis. Teriparatide, an anabolic agent, stimulates bone formation and corrects the characteristic changes in the trabecular microarchitecture. However, these drugs are associated with significant side effects. It is therefore crucial that we continue to research the pathogenesis of osteoporosis and seek novel modes of therapy. This editorial summarizes and discusses the themes of the six articles published in our Special Issue "Osteoporosis: From Molecular Mechanisms to Therapies 3.0", a continuation of our 2020 Special Issue "Osteoporosis: From Molecular Mechanisms to Therapies". These Special Issues detail important global scientific findings that contribute to our current understanding of osteoporosis.

Keywords: molecular mechanisms; osteoporosis; prevention; signaling pathways; treatment.

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Conflict of interest statement

The authors declare no conflict of interest.

References

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