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Case Reports
. 2022 Feb:300:114419.
doi: 10.1016/j.jviromet.2021.114419. Epub 2021 Dec 10.

SARS-Cov-2 pneumonia and concurrent myelodysplasia complicated by Pseudomonas aeruginosa over-infection

Aldo Pezzuto  1 , Antonella Tammaro  2 , Giuseppe Tonini  3 , Giulia Conforti  4 , Francesca Falangone  5 , Valerio Spuntarelli  6 , Antonella Teggi  7 , Alfredo Pennica  8
Affiliations
Case Reports

SARS-Cov-2 pneumonia and concurrent myelodysplasia complicated by Pseudomonas aeruginosa over-infection

Aldo Pezzuto et al. J Virol Methods. 2022 Feb.

Abstract

The new virus called severe acute respiratory syndrome coronavirus 2 (SARSCov-2) causing Coronavirus disease 2019 (COVID-19) has spread quickly in several countries and it has become pandemic. Different types of clinical manifestations are attributed to this infection. Some mechanisms related to the infection regarding the immune response are not still elucidated. Herein we reported a case of a 66-years-old patient affected by myelodysplasia who was referred to our hospital because of clinical and radiological manifestations of viral pneumonia. The clinical course has become complicated due to bacterial secondary over-infection by Pseudomonas aeruginosa during stay in internal medicine unit whilst a persistent positive oral and naso-pharyngeal swab test was reported up to 100 days of admission. The patient had a fast clinical and radiological worsening that led her to be admitted to an intensive care unit. Despite intubation and mechanical ventilation she died in a few days.

Keywords: Bacterial over-infection; Myelodysplasia; SARS-Cov-2 pneumonia.

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
Baseline CT scan of the chest showing infiltrates located in the lower lobes.
Fig. 2
Fig. 2
Following CT scan of the chest after 7 days from the first check showing a significant increase of lung multifocal patchy consolidations.
See this image and copyright information in PMC

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