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Review
. 2022 Jun 1;33(4):1082-1089.
doi: 10.1097/SCS.0000000000008432. Epub 2021 Dec 10.

Algorithmic Approach to Antibiotic Prophylaxis for Traumatic Craniomaxillofacial Injuries

Daniel Phillip Caruso  1 , Vincent Mario Aquino  2 , R John Tannyhill 3rd  1   3
Affiliations
Review

Algorithmic Approach to Antibiotic Prophylaxis for Traumatic Craniomaxillofacial Injuries

Daniel Phillip Caruso et al. J Craniofac Surg. .

Abstract

Prophylactic antibiotics are commonly used in the management of traumatic injuries to the maxillofacial complex, yet there are no set guidelines for when and when not to prescribe. The purpose of this review is to present the evidence for antibiotic prophylaxis in different clinical scenarios and to propose algorithms to facilitate the decision making process with the ultimate goal of improving antibiotic prescribing practices. A number of databases were searched using a wide range of keywords to ensure the topic was fully encapsulated. The review is divided into 3 sections: soft tissue trauma, maxillofacial fractures, and ballistic injuries. The algorithms were constructed using the current evidence as well as pathophysiologic principles, especially when there were insufficient studies. This review found the literature on antibiotic prophylaxis to be highly varied and not standardized. Creating an algorithm for providers to follow will help to set a standard of care and decrease the misuse of antibiotics.

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Conflict of interest statement

The authors report no conflicts of interest.

References

    1. Moran GJ, Talan DA, Abrahamian FM. Antimicrobial prophylaxis for wounds and procedures in the emergency department. Infect Dis Clin North Am 2008; 22:117–143.
    1. Cummings P, Del Beccaro MA. Antibiotics to prevent infection of simple wounds: a meta-analysis of randomized studies. Am J Emerg Med 1995; 13:396–400.
    1. Sirijatuphat R, Siritongtaworn P, Sripojtham V, et al. Bacterial contamination of fresh traumatic wounds at Trauma Center, Siriraj Hospital, Bangkok, Thailand. J Med Assoc Thail Chotmaihet Thangphaet 2014; 97: (Suppl 3): S20–S25.
    1. Torpy JM. Wound infections. JAMA 2005; 294:2122.
    1. Quinn JV, Polevoi SK, Kohn MA. Traumatic lacerations: what are the risks for infection and has the “golden period” of laceration care disappeared? Emerg Med J EMJ 2014; 31:96–100.

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