Nutrition support for critically ill patients
- PMID: 34897737
- DOI: 10.1002/jpen.2228
Nutrition support for critically ill patients
Abstract
Nutrition support is an important aspect of the management of critically ill patients. This review highlights the emerging evidence on critical care nutrition and focuses on the pathophysiologic interplay between critical illness, the gastrointestinal tract, and nutrition support and the evidence on the best route, dose, and timing of nutrition. Although indirect calorimetry is recommended to measure energy expenditure, predictive equations are commonly used but are limited by their inaccuracy in individual patients. The current evidence supports early enteral nutrition (EN) in most patients, with a gradual increase in the daily dose over the first week. Delayed EN is warranted in patients with severe shock. According to recent trials, parenteral nutrition seems to be as effective as EN and may be started if adequate EN is not achieved by the first week of critical illness. A high protein dose has been recommended, but the best timing is unclear. Immuno-nutrition should not be routinely provided to critically ill patients. Patients receiving artificial nutrition should be monitored for metabolic derangements. Additional adequately powered studies are still needed to resolve many unanswered questions.
Keywords: NUTRIC score; calories; critical illness; enteral nutrition; protein.
© 2021 American Society for Parenteral and Enteral Nutrition.
References
REFERENCES
-
- Nicolo M, Heyland DK, Chittams J, Sammarco T, Compher C. Clinical outcomes related to protein delivery in a critically ill population: a multicenter, multinational observation study. JPEN J Parenter Enter Nutr. 2016;40(1):45-51.
-
- Otani S, Coopersmith CM. Gut integrity in critical illness. J Intensive Care. 2019;7(1):1-7.
-
- MacDonald TT, Monteleone I, Fantini MC, Monteleone G. Regulation of homeostasis and inflammation in the intestine. Gastroenterology. 2011;140(6):1768-1775.
-
- Wischmeyer PE, McDonald D, Knight R. Role of the microbiome, probiotics, and ‘dysbiosis therapy'in critical illness. Curr Opin Crit Care. 2016;22(4):347.
-
- Clark JA, Coopersmith CM. Intestinal crosstalk-a new paradigm for understanding the gut as the “motor” of critical illness. Shock. 2007;28(4):384.
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