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Editorial
. 2021 Dec 14;144(24):1912-1914.
doi: 10.1161/CIRCULATIONAHA.121.057533. Epub 2021 Dec 13.

Accelerated Epigenetic Aging and Incident Atrial Fibrillation: New Outlook on an Immutable Risk Factor?

Affiliations
Editorial

Accelerated Epigenetic Aging and Incident Atrial Fibrillation: New Outlook on an Immutable Risk Factor?

Cavin K Ward-Caviness. Circulation. .
No abstract available

Keywords: Editorials; aging; atrial fibrillation; epigenomics; risk factors.

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Conflict of interest statement

Conflict of Interest Disclosures:

Figures

Figure 1
Figure 1
While chronological age progresses at an immutable rate (blue line), biological aging (red line) – measured by epigenetic age in this manuscript – is modifiable by various exposures and life experiences. Thus, establishing a relationship between epigenetic age and atrial fibrillation risk gives a unique insight into modifiable ageing associated atrial fibrillation risks.

Comment on

  • Epigenetic Age and the Risk of Incident Atrial Fibrillation.
    Roberts JD, Vittinghoff E, Lu AT, Alonso A, Wang B, Sitlani CM, Mohammadi-Shemirani P, Fornage M, Kornej J, Brody JA, Arking DE, Lin H, Heckbert SR, Prokic I, Ghanbari M, Skanes AC, Bartz TM, Perez MV, Taylor KD, Lubitz SA, Ellinor PT, Lunetta KL, Pankow JS, Paré G, Sotoodehnia N, Benjamin EJ, Horvath S, Marcus GM. Roberts JD, et al. Circulation. 2021 Dec 14;144(24):1899-1911. doi: 10.1161/CIRCULATIONAHA.121.056456. Epub 2021 Sep 30. Circulation. 2021. PMID: 34587750 Free PMC article. Clinical Trial.

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