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. 2021 Oct 29;28(6):4317-4327.
doi: 10.3390/curroncol28060367.

Report from the Western Canadian Gastrointestinal Cancer Consensus Conference Virtual Education Series-Transition from Local to System Therapy and Optimal Sequencing of Systemic Therapy for HCC

Affiliations

Report from the Western Canadian Gastrointestinal Cancer Consensus Conference Virtual Education Series-Transition from Local to System Therapy and Optimal Sequencing of Systemic Therapy for HCC

Adnan Zaidi et al. Curr Oncol. .

Abstract

The Western Canadian Gastrointestinal Cancer Consensus Conference (WC-5) convened virtually on 10 February 2021. The WC-5 is an interactive multidisciplinary conference attended by health care professionals from across Western Canada (British Columbia, Alberta, Saskatchewan, and Manitoba) who are involved in the care of patients with gastrointestinal cancer. Surgical, medical, and radiation oncologists; pathologists; radiologists; and allied health care professionals participated in presentation and discussion sessions for the purpose of developing the recommendations presented here. This consensus statement addresses current issues in the management of hepatocellular cancer (HCC). Recommendations have been made for the transition from local to systemic therapy and the optimal sequencing of systemic regimens in the management of HCC.

Keywords: SABR; TACE; hepatocellular cancer; immunotherapy; local therapy; systemic therapy.

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Conflict of interest statement

J.D. has conducting clinical trials for BMS, Merck, MedImmune and Astellas Array BioPharma, and is a consultant for AstraZeneca, Eisai, Taiho and Amgen. C.K. received an unrelated research grant from Celgene Inc. and an honorarium from Amgen. H.L. received honoraria from Merck, BMS, AstraZeneca, Eisai, Taiho, Roche, Amgen and Bayer for consultant work. D.L. is a consultant for Sirtex Medical and AstraZeneca, both a speaker and consultant for Eisai, and a speaker for Ethicon Endosurgery. R.L.-Y. has had advisory roles for Eisai, Ipsen, AstraZeneca, Roche and Celgene. K.M. has an advisory role for Pfizer Canada, Eisai Inc. and Bayer Canada and has received clinical trials funding from Deciphera Pharmaceuticals, BluePrint Medicines and AstraZeneca. D.S. has received grant funding from Varian Medical, honoraria from AstraZeneca, Merck and Pfizer, and is on the advisory board for AstraZeneca. A.Z. has received travel grants from Roche and has also performed consultant work for Eisai. The remaining authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
Local–regional therapy flow chart.
Figure 2
Figure 2
Systemic therapy flow chart.

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