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Case Reports
. 2021 Nov 3;13(11):e19242.
doi: 10.7759/cureus.19242. eCollection 2021 Nov.

Unusual Lower Lip Swelling: A Rare Case of Lip Schwannoma

Mohamad Bakir  1 , Joud Enabi  1 , Hanan Almeshal  2
Affiliations
Case Reports

Unusual Lower Lip Swelling: A Rare Case of Lip Schwannoma

Mohamad Bakir et al. Cureus. .

Abstract

Schwannoma (neurilemmoma) is a benign neoplasm that arises from the nerve sheath's Schwann cells. Between 25% and 40% of all schwannomas are discovered in the soft tissues of the head and neck area, but they are infrequently detected in the oral cavity, with the lips being the most unusual site of involvement. Peripheral nerves in the intraoral cavity originate only 1% of schwannomas despite the fact that lips and oral cavity are heavily innervated anatomical areas. Schwannomas are more common in people between the third and fifth decades of life, and there is no predilection based on gender or race. Here, we report a case of lip schwannomas in a 22-year-old female. The lesion was affecting her lower lip and growing steadily for the past two years. The mass measured 1.5 x 1 cm, involving the lower lip with surface telangiectasia. The patient underwent surgical removal of the lower lip mass, and the mass was sent for histopathological correlation that showed completely excised encapsulated schwannoma with free margins. The patient did not have any postoperative complications and was discharged home on the same day. The patient was followed up in the outpatient clinics, and she made full recovery and was pleased with the outcome.

Keywords: case report; lower lip; neurilemmoma; neurofibroma; oral neural neoplasms; schwannoma; verocay bodies.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Preoperative image showing single skin-colored firm lower lip mass with surface telangiectasia
Figure 2
Figure 2. Histopathology slide showing biphasic compact hypercellular Antoni A areas and myxoid hypocellular Antoni B areas with nuclear palisading around the fibrillary process (Verocay bodies)
Figure 3
Figure 3. Histopathology slide showing diffuse S100 staining consistent with schwannoma
Figure 4
Figure 4. Histopathology slide showing negative cluster of differentiation 34 (CD34) stain (positive in the blood vessels internal control)
Figure 5
Figure 5. Histopathology slide showing negative smooth muscle actin (SMA) stain (positive in the blood vessels internal control)
Figure 6
Figure 6. Postoperative image showing the lower lip after full removal of the tumor
See this image and copyright information in PMC

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