Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2021 Dec 2:2021:9774980.
doi: 10.1155/2021/9774980. eCollection 2021.

Acute Whole-Body Vibration Exercise Promotes Favorable Handgrip Neuromuscular Modifications in Rheumatoid Arthritis: A Cross-Over Randomized Clinical

Ana Carolina Coelho-Oliveira  1   2   3   4 , Ana Cristina Rodrigues Lacerda  1   2   3 , Ana Lúcia Cristino de Souza  1 , Luciana Martins de Mello Santos  1   2   3 , Sueli Ferreira da Fonseca  1   3 , Jousielle Márcia Dos Santos  1   3 , Vanessa Gonçalves César Ribeiro  1   3 , Hércules Ribeiro Leite  1   2   3 , Pedro Henrique Scheidt Figueiredo  1   2   3 , José Sebastião Cunha Fernandes  5 , Fábio Martins  1   2   3 , Renato Guilherme Trede Filho  1   2   3 , Mario Bernardo-Filho  4 , Danúbia da Cunha de Sá-Caputo  4 , Alessandro Sartorio  6 , Darryl Cochrane  7 , Vanessa Pereira Lima  1   2   3 , Henrique Silveira Costa  1   2   3 , Vanessa Amaral Mendonça  1   2   3 , Redha Taiar  8
Affiliations
Randomized Controlled Trial

Acute Whole-Body Vibration Exercise Promotes Favorable Handgrip Neuromuscular Modifications in Rheumatoid Arthritis: A Cross-Over Randomized Clinical

Ana Carolina Coelho-Oliveira et al. Biomed Res Int. .

Abstract

Objective: Rheumatoid arthritis (RA) causes progressive changes in the musculoskeletal system compromising neuromuscular control especially in the hands. Whole-body vibration (WBV) could be an alternative for the rehabilitation in this population. This study investigated the immediate effect of WBV while in the modified push-up position on neural ratio (NR) in a single session during handgrip strength (HS) in women with stable RA.

Methods: Twenty-one women with RA (diagnosis of disease: ±8 years, erythrocyte sedimentation rate: ±24.8, age: 54± 11 years, BMI: 28 ± 4 kg·m-2) received three experimental interventions for five minutes in a randomized and balanced cross-over order: (1) control-seated with hands at rest, (2) sham-push-up position with hands on the vibration platform that remained disconnected, and (3) vibration-push-up position with hands on the vibration platform turned on (45 Hz, 2 mm, 159.73 m·s-2). At the baseline and immediately after the three experimental interventions, the HS, the electromyographic records (EMGrms), and range of motion (ROM) of the dominant hand were measured. The NR, i.e., the ratio between EMGrms of the flexor digitorum superficialis (FDS) muscle and HS, was also determined. The lower NR represented the greater neuromuscular efficiency (NE).

Results: The NR was similar at baseline in the three experimental interventions. Despite the nonsignificance of within-interventions (p = 0.0611) and interaction effect (p = 0.1907), WBV exercise reduced the NR compared with the sham and control (p = 0.0003, F = 8.86, η 2 = 0.85, power = 1.00).

Conclusion: Acute WBV exercise under the hands promotes neuromuscular modifications during the handgrip of women with stable RA. Thus, acute WBV exercise may be used as a preparatory exercise for the rehabilitation of the hands in this population. This trial is registered with trial registration 2.544.850 (ReBEC-RBR-2n932c).

PubMed Disclaimer

Conflict of interest statement

The authors declare that there is no conflict of interest regarding the publication of this paper.

Figures

Figure 1
Figure 1
Flow of participants through the study.
Figure 2
Figure 2
Study design.
Figure 3
Figure 3
Experimental intervention positions. (a) Control position and (b) push-up position adopted during sham or WBV exercise interventions.
Figure 4
Figure 4
Neural ratio at baseline and after the experimental interventions. ∗p < 0.05.
See this image and copyright information in PMC

References

    1. Garg A., the WISTAH Hand Study Team, Hegmann K. T., et al. The WISTAH hand study: a prospective cohort study of distal upper extremity musculoskeletal disorders. BMC Musculoskeletal Disorders . 2012;13(1) doi: 10.1186/1471-2474-13-90. - DOI - PMC - PubMed
    1. Plasqui G. The role of physical activity in rheumatoid arthritis. Physiology & Behavior . 2008;94(2):270–275. doi: 10.1016/j.physbeh.2007.12.012. - DOI - PubMed
    1. Prioreschi A., Tikly M., McVeigh J. A. A three month controlled intervention of intermittent whole body vibration designed to improve functional ability and attenuate bone loss in patients with rheumatoid arthritis. BMC Musculoskeletal Disorders . 2014;15(1) doi: 10.1186/1471-2474-15-403. - DOI - PMC - PubMed
    1. Sangha O. Epidemiology of rheumatic diseases. Rheumatology (Oxford) . 2000;39(supplement 2):3–12. doi: 10.1093/rheumatology/39.suppl_2.3. - DOI - PubMed
    1. Corbacho M. I., Dapueto J. J. Assessing the functional status and quality of life of patients with rheumatoid arthritis. Revista Brasileira de Reumatologia . 2010;50(1):31–43. doi: 10.1590/S0482-50042010000100004. - DOI - PubMed

Publication types