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. 2021 Dec;32(4):789-796.
doi: 10.1007/s13337-021-00748-6. Epub 2021 Oct 29.

First complete genome characterization of duck plague virus from India

Ashutosh Aasdev  1 , Satyam D Pawar  1   2 , Anamika Mishra  1 , Chandan K Dubey  1 , Sharan S Patil  3 , Sophia M Gogoi  4 , Durlav P Bora  4 , Nagendra N Barman  4 , Ashwin A Raut  1   5
Affiliations

First complete genome characterization of duck plague virus from India

Ashutosh Aasdev et al. Virusdisease. 2021 Dec.

Abstract

In this study, we report the complete genome sequencing of the Duck plague virus from India for the first time. The sequencing was done on the MinION nanopore sequencer from Oxford Nanopore Technologies. The closest relative is the European strain 2085v, with 99.98 and 99.8% identity at the amino acid and nucleotide level respectively. Moreover, 72 out of 77 ORFs are completely conserved between the 2 strains. The high similarity with the European strain over the only three other pathogenic strains reported from China points to the circulation of European strain in India. The fly pathways of migratory birds and co-habitation with native species being a probable reason. More complete genome data from diverse sampling locations are needed to characterize the genomic features, develop diagnostics, vaccines, and understand the evolution of the virus.

Keywords: Anatid alphaherpesvirus 1; Duck plague; Duck viral enteritis; Nanopore sequencing; North-eastern India.

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Conflict of interest statement

Conflict of interestThe authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.

Figures

Fig. 1
Fig. 1
Genome map of the duck plague virus sequenced. The genome is shown as double stranded. The blue colored ORFs are 100% identical to strain 2085v while the orange ones show some divergence. The genome regions are colored in pink
See this image and copyright information in PMC

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