Micro- and nanoplastic transfer, accumulation, and toxicity in humans
- PMID: 34901583
- PMCID: PMC8654083
- DOI: 10.1016/j.cotox.2021.10.001
Micro- and nanoplastic transfer, accumulation, and toxicity in humans
Abstract
Plastics impact our daily lives. Unfortunately, it is the disuse and disposal of these items that may affect us the greatest. Plastic micro- and nanosized particles, likely from bulk degradation, have been identified in air pollution and water sources. Recently, plastic particles have also been identified in consumable products. The purpose of this review is to identify the likely routes of human exposure, the toxicological outcomes and concerns currently reported, and to provide some considerations for future assessments.
Keywords: exposure; microplastic; nanoplastic; toxicity.
Conflict of interest statement
Declaration of interests The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
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References
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- Zhang K, Hamidian AH, Tubić A, Zhang Y, Fang JKH, Wu C, Lam PKS: Understanding plastic degradation and microplastic formation in the environment: A review. Environ Pollut (2021) 274(116554. - PubMed
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*Campanale C, Massarelli C, Savino I, Locaputo V, Uricchio VF: A detailed review study on potential effects of microplastics and additives of concern on human health. Int J Environ Res Public Health (2020) 17(4).
*While providing a review of current literature, the authors focus on the plastics acting as a vector for human exposure to chemically added (i.e. plasticizers) or environmentally adhered (i.e., metals) toxicants.
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*Cox KD, Covernton GA, Davies HL, Dower JF, Juanes F, Dudas SE: Human consumption of microplastics. Environmental science & technology (2019) 53(12):7068–7074.
**This is the first paper to unify microplastic measurements in environmental and consumable products to estimate human exposure. Authors further separate exposures to men, women, and children.
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