Mental health before and during the pandemic in people with systemic sclerosis

Richard S Henry^{1

2}, Linda Kwakkenbos^{3

4}, Marie-Eve Carrier¹, Zelalem Negeri^{1

5}, Angelica Bourgeault¹, Scott Patten^{6

7

8}, Susan J Bartlett^{9

10}, Luc Mouthon^{11

12}, John Varga¹³, Andrea Benedetti¹⁴, Brett D Thombs^{1

2

5

9

15

16

17}; SPIN COVID-19 Patient Advisory Team; SPIN investigators

Affiliations

¹ Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, QC H3T 1E4, Canada.
² Department of Psychiatry, McGill University, Montreal, QC, Canada.
³ Department of Clinical Psychology, Radboud University, Nijmegen, Netherlands.
⁴ Department of Medical Psychology, Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, Netherlands.
⁵ Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, QC, Canada.
⁶ Department of Community Health Sciences, University of Calgary, Calgary, AB, Canada.
⁷ Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada.
⁸ O'Brien Institute for Public Health, University of Calgary, Calgary, AB, Canada.
⁹ Department of Medicine, McGill University, Montreal, QC, Canada.
¹⁰ Research Institute of the McGill University Health Centre, Montreal, QC, Canada.
¹¹ Service de Médecine Interne, Centre de Référence Maladies Autoimmunes Systémiques Rares d'Ile de France, Hôpital Cochin, Assistance Publique-Hôpitaux de Paris, Paris, France.
¹² APHP-CUP, Hôpital Cochin, Université de Paris, Paris, France.
¹³ Department of Medicine, Division of Rheumatology, University of Michigan, Ann Arbor, MI, USA.
¹⁴ Respiratory Epidemiology and Clinical Research Unit, McGill University Health Centre, Montreal, QC, Canada.
¹⁵ Department of Psychology, McGill University, Montreal, QC, Canada.
¹⁶ Department of Educational and Counselling Psychology, McGill University, Montreal, QC, Canada.
¹⁷ Biomedical Ethics Unit, McGill University, Montreal, QC, Canada.

PMID: 34901884
PMCID: PMC8641958
DOI: 10.1016/S2665-9913(21)00363-5

Mental health before and during the pandemic in people with systemic sclerosis

Richard S Henry et al. Lancet Rheumatol. 2022 Feb.

. 2022 Feb;4(2):e82-e85.

doi: 10.1016/S2665-9913(21)00363-5. Epub 2021 Dec 3.

Authors

Affiliations

¹ Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, QC H3T 1E4, Canada.
² Department of Psychiatry, McGill University, Montreal, QC, Canada.
³ Department of Clinical Psychology, Radboud University, Nijmegen, Netherlands.
⁴ Department of Medical Psychology, Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, Netherlands.
⁵ Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, QC, Canada.
⁶ Department of Community Health Sciences, University of Calgary, Calgary, AB, Canada.
⁷ Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada.
⁸ O'Brien Institute for Public Health, University of Calgary, Calgary, AB, Canada.
⁹ Department of Medicine, McGill University, Montreal, QC, Canada.
¹⁰ Research Institute of the McGill University Health Centre, Montreal, QC, Canada.
¹¹ Service de Médecine Interne, Centre de Référence Maladies Autoimmunes Systémiques Rares d'Ile de France, Hôpital Cochin, Assistance Publique-Hôpitaux de Paris, Paris, France.
¹² APHP-CUP, Hôpital Cochin, Université de Paris, Paris, France.
¹³ Department of Medicine, Division of Rheumatology, University of Michigan, Ann Arbor, MI, USA.
¹⁴ Respiratory Epidemiology and Clinical Research Unit, McGill University Health Centre, Montreal, QC, Canada.
¹⁵ Department of Psychology, McGill University, Montreal, QC, Canada.
¹⁶ Department of Educational and Counselling Psychology, McGill University, Montreal, QC, Canada.
¹⁷ Biomedical Ethics Unit, McGill University, Montreal, QC, Canada.

PMID: 34901884
PMCID: PMC8641958
DOI: 10.1016/S2665-9913(21)00363-5

No abstract available

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Conflict of interest statement

RSH, LK, M-EC, SP, SJB, LM, JV, ABe, BDT, and members of the SPIN-COVID-19 patient advisory team were responsible for study concept and design. RSH, LK, M-EC, ABo, ABe, and BDT were responsible for data acquisition. RSH and LK directly accessed and verified the data. RSH, ZN, and ABe were responsible for statistical analysis. RSH and BDT drafted the manuscript. All authors provided critical revision of the manuscript for important intellectual content, approved the final version, and agree to be accountable for all aspects of the work. LM reports personal fees from Actelion/Johnson & Johnson; grants from LFB; non-financial support from Octapharma; and non-financial support from Grifols, all outside the submitted work. All other authors declare no competing interests. De-identified individual participant data with a data dictionary and analysis codes that were used to generate the results reported in this Comment will be made available upon request to the corresponding author and presentation of a methodologically sound proposal that is approved by the SPIN data access and publications committee. Data will be available after publication. Data requesters will need to sign a data transfer agreement. The study was funded by the Canadian Institutes of Health Research (number VR4-172745, GA4-177764), McGill Interdisciplinary Initiative in Infection and Immunity Emergency COVID-19 Research Fund; Scleroderma Canada, made possible by an educational grant for patient support programming from Boehringer Ingelheim; Scleroderma Society of Ontario; Scleroderma Manitoba; Scleroderma Atlantic; Scleroderma Australia; Scleroderma New South Wales; Scleroderma Victoria; Scleroderma Queensland; Scleroderma SASK; Scleroderma Association of BC; and Sclérodermie Québec. RSH and ZN were supported by Mitacs post-doctoral fellowship awards, ABe was supported by a Fonds de recherche du Québec—Santé senior researcher salary award, and BDT was supported by a tier 1 Canada Research Chair, all outside of the submitted work. No sponsor had any role in the study design, data collection, data analysis, or interpretation, writing of the report, or in the decision to submit for publication.

Figures

**Figure**
Anxiety and depression scores before and during the COVID-19 pandemic Mean anxiety (A) and depression (C) symptom scores with 95% CIs for the SPIN Cohort subsample before the COVID-19 pandemic and at each assessment during the pandemic. Mean anxiety (B) and depression (D) symptom scores with 95% CIs for those who completed ten or more assessments. Anxiety was scored with PROMIS Anxiety 4a version 1.0 and depression was scored with the eight-item Patient Health Questionnaire. For number of participants at each timepoint see the appendix (p 7).

See this image and copyright information in PMC

References

1. WHO Impact of COVID-19 on people's livelihoods, their health and our food systems: joint statement by ILO, FAO, IFAD and WHO. https://www.who.int/news/item/13-10-2020-impact-of-covid-19-on-people%27...
1. Holmes EA, O'Connor RC, Perry VH, et al. Multidisciplinary research priorities for the COVID-19 pandemic: a call for action for mental health science. Lancet Psychiatry. 2020;7:547–560. - PMC - PubMed
1. Sun Y, Wu Y, Bonardi O, et al. Comparison of mental health symptoms prior to and during COVID-19: evidence from a living systematic review and meta-analysis. MedRxiv. 2021 doi: 10.1101/2021.05.10.21256920. published online May 11. (preprint). - DOI
1. Allanore Y, Simms R, Distler O, et al. Systemic sclerosis. Nat Rev Dis Primers. 2015;1:15002. - PubMed
1. Dougherty DH, Kwakkenbos L, Carrier ME, et al. The scleroderma patient-centered intervention network cohort: baseline clinical features and comparison with other large scleroderma cohorts. Rheumatol. 2018;57:1623–1631. - PubMed

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Mental health before and during the pandemic in people with systemic sclerosis

Affiliations

Mental health before and during the pandemic in people with systemic sclerosis

Authors

Affiliations

Conflict of interest statement

Figures

References

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