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. 2022 Feb;63(1):81-85.
doi: 10.1111/ajd.13759. Epub 2021 Dec 14.

Pigmented purpuric dermatoses versus purpuric mycosis fungoides: Clinicopathologic similarities and new insights into dermoscopic features

Maryam Nasimi  1 , Masoud Bonabiyan  1 , Vahideh Lajevardi  1 , Arghavan Azizpour  1 , Afsaneh Nejat  1 , Shayan Dasdar  1 , Nika Kianfar  1
Affiliations

Pigmented purpuric dermatoses versus purpuric mycosis fungoides: Clinicopathologic similarities and new insights into dermoscopic features

Maryam Nasimi et al. Australas J Dermatol. 2022 Feb.

Abstract

Background: The diagnosis of purpuric mycosis fungoides (PMF) is often challenging to be clinically differentiated from inflammatory diseases such as pigmented purpuric dermatosis (PPD). Dermoscopy as a non-invasive method can be employed for the visualisation of features invisible to the naked eye.

Objectives: This study aimed to survey the dermoscopic findings of PMF in comparison with PPD.

Methods: Forty-one patients with an established diagnosis of PMF (n = 28) and PPD (n = 13) were prospectively recruited. Dermoscopic images were taken by FotoFinder Medicam 1000 (FotoFinder Systems GmbH, Bad Birnbach, Germany).

Results: Characteristic dermoscopic patterns consisting of fine short linear vessels (35.7%, P = 0.017) and spermatozoa-like structures (50%, P = 0.014) were found to be significantly more common in PMF lesions, while PPD lesions were typified by erythematous globules (76.9%, P = 0.01), in the background colour of dull red (61.5%, P = 0.01) and reticular pigmentation (61.5%, P = 0.044).

Conclusions: This study showed the usefulness of dermoscopy for the diagnosis of PMF and PPD cases. Studies with long-term follow-up are needed to affirm the value of these dermoscopic patterns in the differentiation between the two entities.

Keywords: dermatoscopy; dermoscopy; epiluminescence; mycosis fungoides; pigmented purpuric dermatosis.

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