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. 2021 Dec 1;4(12):e2138975.
doi: 10.1001/jamanetworkopen.2021.38975.

Estimated Effectiveness of COVID-19 Messenger RNA Vaccination Against SARS-CoV-2 Infection Among Older Male Veterans Health Administration Enrollees, January to September 2021

Yinong Young-Xu  1   2 , Gabrielle M Zwain  1 , Ethan I Powell  1 , Jeremy Smith  1
Affiliations

Estimated Effectiveness of COVID-19 Messenger RNA Vaccination Against SARS-CoV-2 Infection Among Older Male Veterans Health Administration Enrollees, January to September 2021

Yinong Young-Xu et al. JAMA Netw Open. .

Abstract

This case-control study examines estimated COVID-19 messenger RNA vaccination effectiveness against SARS-CoV-2 infection from January to September 2021 among fully vaccinated male veterans aged 65 years or older.

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Conflict of interest statement

Conflict of Interest Disclosures: Dr Young-Xu and Mr Smith reported receiving funding from Pfizer. Ms Zwain reported receiving grants from the US Food and Drug Administration through an interagency agreement with the Veterans Health Administration and from the US Department of Veterans Affairs Office of Rural Health. Ms Zwain also reported receiving funding from Pfizer to her employer for other research projects outside the submitted work. Mr Powell reported receiving grants from the US Department of Veterans Affairs Office of Rural Health, the US Food and Drug Administration, and Pfizer. No other disclosures were reported.

Figures

Figure.
Figure.. Estimated Messenger RNA Vaccine Effectiveness Against SARS-CoV-2 Infection by Delta Variant Period, January to September 2021
See this image and copyright information in PMC

References

    1. Young-Xu Y, Korves C, Roberts J, et al. . Coverage and estimated effectiveness of mRNA COVID-19 vaccines among US veterans. JAMA Netw Open. 2021;4(10):e2128391. doi:10.1001/jamanetworkopen.2021.28391 - DOI - PMC - PubMed
    1. Chemaitelly H, Tang P, Hasan MR, et al. . Waning of BNT162b2 vaccine protection against SARS-CoV-2 infection in Qatar. N Engl J Med. 2021. doi:10.1056/NEJMoa2114114 - DOI - PMC - PubMed
    1. Centers for Disease Control and Prevention . Variants and genomic surveillance for SARS-CoV-2. Updated April 2, 2021. Accessed October 12, 2021. https://www.cdc.gov/coronavirus/2019-ncov/variants/
    1. Bajema KL, Dahl RM, Prill MM, et al. ; SUPERNOVA COVID-19; Surveillance Group; Surveillance Platform for Enteric and Respiratory Infectious Organisms at the VA (SUPERNOVA) COVID-19 Surveillance Group . Effectiveness of COVID-19 mRNA vaccines against COVID-19-associated hospitalization—five Veterans Affairs medical centers, United States, February 1-August 6, 2021. MMWR Morb Mortal Wkly Rep. 2021;70(37):1294-1299. doi:10.15585/mmwr.mm7037e3 - DOI - PMC - PubMed

Publication types

Supplementary concepts