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. 2021 Dec 15;9(12).
doi: 10.2106/JBJS.RVW.21.00082.

Double Crush Syndrome of the Upper Extremity

Amy Phan  1 , Shalin Shah, Warren Hammert, Addisu Mesfin
Affiliations

Double Crush Syndrome of the Upper Extremity

Amy Phan et al. JBJS Rev. .

Abstract

»: The double crush hypothesis originally proposed that compression of a peripheral nerve at a proximal site increases its susceptibility to additional distal lesions.

»: The etiology of double crush syndrome is likely multifactorial as mechanical, systemic, pharmacologic, or environmental factors may increase a patient's susceptibility to this syndrome.

»: To date, there remains no standardized definition of double crush syndrome, and there is no consensus on its exact pathophysiology or diagnostic criteria.

»: Patients with double crush syndrome should be counseled that surgical repair may produce inferior outcomes compared with those who are treated for isolated entrapment neuropathies.

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Conflict of interest statement

Disclosure: The Disclosure of Potential Conflicts of Interest forms are provided with the online version of the article (http://links.lww.com/JBJSREV/A787).

References

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