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Comment
. 2021 Dec 14;54(12):2690-2692.
doi: 10.1016/j.immuni.2021.11.013.

Tfh cells set the stage for tumor control

Cecile King  1
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Free article
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Tfh cells set the stage for tumor control

Cecile King. Immunity. .
Free article

Abstract

The microbiome has a profound influence on the development and progression of cancer, as well as the response to immunotherapy. In this issue of Immunity, Overacre-Delgoffe et al. (2021) examine the impact of the immunogenic bacteria Helicobacter hepaticus (Hhep) in the immune response to colorectal cancer, providing evidence that T follicular helper (Tfh) cells that specifically recognize Hhep antigens are necessary for the control of tumor growth.

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