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Comment
. 2021 Dec 14;54(12):2698-2700.
doi: 10.1016/j.immuni.2021.11.014.

Enteric glia worm their way into gut immunity

Meenakshi Rao  1 , Milena Bogunovic  2
Affiliations
Free article
Comment

Enteric glia worm their way into gut immunity

Meenakshi Rao et al. Immunity. .
Free article

Abstract

The gut houses one of the largest populations of glia in the nervous system, yet their essential functions remain unclear. New work by Progatzky et al. (2021) in Nature reveals that these enteric glia orchestrate an IFNγ-dependent immune response to helminth infection that promotes tissue repair.

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  • Regulation of intestinal immunity and tissue repair by enteric glia.
    Progatzky F, Shapiro M, Chng SH, Garcia-Cassani B, Classon CH, Sevgi S, Laddach A, Bon-Frauches AC, Lasrado R, Rahim M, Amaniti EM, Boeing S, Shah K, Entwistle LJ, Suárez-Bonnet A, Wilson MS, Stockinger B, Pachnis V. Progatzky F, et al. Nature. 2021 Nov;599(7883):125-130. doi: 10.1038/s41586-021-04006-z. Epub 2021 Oct 20. Nature. 2021. PMID: 34671159 Free PMC article.

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