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. 2022 Jun;93(6):681-682.
doi: 10.1136/jnnp-2021-327877. Epub 2021 Dec 15.

Prognostic relationship of neurofilaments, CHIT1, YKL-40 and MCP-1 in amyotrophic lateral sclerosis

Pegah Masrori  1   2 , Maxim De Schaepdryver  3 , Mary Kay Floeter  4 , Joke De Vocht  1   2 , Nikita Lamaire  1 , Ann D'Hondt  1 , Bryan Traynor  4   5   6 , Koen Poesen  3   7 , Philip Van Damme  8   2
Affiliations

Prognostic relationship of neurofilaments, CHIT1, YKL-40 and MCP-1 in amyotrophic lateral sclerosis

Pegah Masrori et al. J Neurol Neurosurg Psychiatry. 2022 Jun.
No abstract available

Keywords: ALS; C9ORF; CSF.

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Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
Combination of NfL and YKL-40 levels to predict survival in patients with amyotrophic lateral sclerosis. Scatter plot of survival in patients with amyotrophic lateral sclerosis (ALS) based on the biomarker profile of neurofilament light (NfL) and chitinase‐3-like protein 1 (YKL‐40) levels in cerebrospinal fluid (CSF) (A). Patients with ALS were classified as high and low according to the median concentration of the specific biomarker. Kruskal-Wallis test with Dunn’s post hoc test, ****p<0.0001. Kaplan-Meier survival curves of patients with ALS classified according to the biomarker profile (B).
See this image and copyright information in PMC

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