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Comment
. 2022 Feb;19(2):73-74.
doi: 10.1038/s41571-021-00590-1.

Cerebrospinal fluid liquid biopsies for medulloblastoma

Joan Seoane  1   2   3   4 , Laura Escudero  5
Affiliations
Comment

Cerebrospinal fluid liquid biopsies for medulloblastoma

Joan Seoane et al. Nat Rev Clin Oncol. 2022 Feb.
No abstract available

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Comment on

  • Serial assessment of measurable residual disease in medulloblastoma liquid biopsies.
    Liu APY, Smith KS, Kumar R, Paul L, Bihannic L, Lin T, Maass KK, Pajtler KW, Chintagumpala M, Su JM, Bouffet E, Fisher MJ, Gururangan S, Cohn R, Hassall T, Hansford JR, Klimo P Jr, Boop FA, Stewart CF, Harreld JH, Merchant TE, Tatevossian RG, Neale G, Lear M, Klco JM, Orr BA, Ellison DW, Gilbertson RJ, Onar-Thomas A, Gajjar A, Robinson GW, Northcott PA. Liu APY, et al. Cancer Cell. 2021 Nov 8;39(11):1519-1530.e4. doi: 10.1016/j.ccell.2021.09.012. Epub 2021 Oct 21. Cancer Cell. 2021. PMID: 34678152 Free PMC article.

References

    1. Hovestadt, V. et al. Medulloblastomics revisited: biological and clinical insights from thousands of patients. Nat. Rev. Cancer 20, 42–56 (2020). - DOI
    1. Diaz, L. A. Jr & Bardelli, A. Liquid biopsies: genotyping circulating tumor DNA. J. Clin. Oncol. 32, 579–586 (2014). - DOI
    1. De Mattos-Arruda, L. et al. Cerebrospinal fluid-derived circulating tumour DNA better represents the genomic alterations of brain tumours than plasma. Nat. Commun. 6, 8839 (2015). - DOI
    1. Martínez-Ricarte, F. et al. Molecular diagnosis of diffuse gliomas through sequencing of cell-free circulating tumor DNA from cerebrospinal fluid. Clin. Cancer Res. 24, 2812–2819 (2018). - DOI
    1. Escudero, L. et al. Circulating tumour DNA from the cerebrospinal fluid allows the characterisation and monitoring of medulloblastoma. Nat. Commun. 11, 5376 (2020). - DOI

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