Sedation, Neuromuscular Blockade, and Mortality in Acute Respiratory Distress Syndrome: Important Questions Remain
- PMID: 34914654
- DOI: 10.1097/CCM.0000000000005258
Sedation, Neuromuscular Blockade, and Mortality in Acute Respiratory Distress Syndrome: Important Questions Remain
Conflict of interest statement
Dr. Dieffenbach received support for article research from the National Institutes of Health. The remaining authors have disclosed that they do not have any potential conflicts of interest.
Comment in
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The authors reply.Crit Care Med. 2022 Jan 1;50(1):e91-e92. doi: 10.1097/CCM.0000000000005329. Crit Care Med. 2022. PMID: 34914655 No abstract available.
Comment on
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Optimal Sedation in Patients Who Receive Neuromuscular Blocking Agent Infusions for Treatment of Acute Respiratory Distress Syndrome-A Retrospective Cohort Study From a New England Health Care Network.Crit Care Med. 2021 Jul 1;49(7):1137-1148. doi: 10.1097/CCM.0000000000004951. Crit Care Med. 2021. PMID: 33710031
References
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- Wongtangman K, Grabitz SD, Hammer M, et al.; SICU Optimal Mobilization Team (SOMT) Group. Optimal Sedation in Patients Who Receive Neuromuscular Blocking Agent Infusions for Treatment of Acute Respiratory Distress Syndrome-A Retrospective Cohort Study From a New England Health Care Network. Crit Care Med. 2021; 49:1137–1148
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- Tarazan N, Alshehri M, Sharif S, et al.; GUIDE Group. Neuromuscular blocking agents in acute respiratory distress syndrome: Updated systematic review and meta-analysis of randomized trials. Intensive Care Med Exp. 2020; 8:61
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- Devlin JW, Skrobik Y, Gélinas C, et al. Clinical practice guidelines for the prevention and management of pain, agitation/sedation, delirium, immobility, and sleep disruption in adult patients in the ICU. Crit Care Med. 2018; 46:e825–e873
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- Shehabi Y, Bellomo R, Kadiman S, et al.; Sedation Practice in Intensive Care Evaluation (SPICE) Study Investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group. Sedation intensity in the first 48 hours of mechanical ventilation and 180-day mortality: A multinational prospective longitudinal cohort study. Crit Care Med. 2018; 46:850–859
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- Slutsky AS, Villar J. Early paralytic agents for ARDS? Yes, no, and sometimes. N Engl J Med. 2019; 380:2061–2063
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