Nivolumab and sorafenib in hepatocellular carcinoma: lessons from the CheckMate 459 study
- PMID: 34914890
- DOI: 10.1016/S1470-2045(21)00651-3
Nivolumab and sorafenib in hepatocellular carcinoma: lessons from the CheckMate 459 study
Conflict of interest statement
MR reports a consultancy from Bayer, Bristol Myers Squibb, Roche, Ipsen, Astra Zeneca, Boston Science, Lilly, and UniversalDX; lecture fees from Bayer, Bristol Myers Squibb, Gilead, Lilly, and ROCHE; travel support from Bayer, Bristol Myers Squibb, Lilly, and AstraZeneca; and research funding (paid to the institution) from Bayer and Ipsen. MR also received grant support from Instituto de Salud Carlos III (PI15/00145 and PI18/0358) and the Spanish Health Ministry (National Strategic Plan against Hepatitis C). MS-Z received speaker fees from Bayer and travel grants from Bayer, BTG, and Eisai-Merck Sharpe and Dohme; was supported by Ajuts per a la iniciació a la recerca 2019 from Societat Catalana de Digestologia (SCD); and received grant support from Instituto de Salud Carlos III (FI19/00222). Both authors are members of the European Reference Network (ERN) RARE-LIVER.
Comment on
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Nivolumab versus sorafenib in advanced hepatocellular carcinoma (CheckMate 459): a randomised, multicentre, open-label, phase 3 trial.Lancet Oncol. 2022 Jan;23(1):77-90. doi: 10.1016/S1470-2045(21)00604-5. Epub 2021 Dec 13. Lancet Oncol. 2022. PMID: 34914889 Clinical Trial.
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