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. 2022 Feb;35(1):76-79.
doi: 10.37201/req/091.2021. Epub 2021 Dec 17.

Mycoplasma genitalium and sexually transmitted infections: evidences and figures in a tertiary hospital

G Martín-Saco, A Tristancho, A Arias, I Ferrer, A Milagro, J M García-Lechuz  1
Affiliations

Mycoplasma genitalium and sexually transmitted infections: evidences and figures in a tertiary hospital

G Martín-Saco et al. Rev Esp Quimioter. 2022 Feb.

Abstract
in English, Spanish

Objective: Mycoplasma genitalium is an emerging cause of sexually transmitted infections (STIs) and has been implicated in non-gonococcal urethritis in men and cervicitis in woman. The aim of this study is determinate the incidence and pathogenicity of M. genitalium within the diagnosis of STIs detected from clinical samples in a third level hospital.

Methods: A total of 8,473 samples from endocervix, urethra, vagina, rectum and others were processed applying Allpex STI Essential Assay. More than 190 records were reviewed to determinate M. genitalium pathogenicity.

Results: M. genitalium was detected in a rate 2.8%. Co-infections were detected in 20% of the patients.

Conclusions: M. genitalium is considered a STI emerging pathogen thanks to the renewal of multiplex-PCR tests although with a low incidence in our approach. Emerging from our experience and the institutional recommendations both detection of acid nucleic techniques (NAATs) and gonococcal culture might be implemented accurately and coexist to adequate prescriptions.

Introducción: Mycoplasma genitalium es un patógeno emergente causante de infecciones de transmisión sexual (ITS) y se ha relacionado con uretritis no gonocócica en hombres y cervicitis en mujeres. El objetivo de este estudio es determinar la incidencia y patogenicidad de M. genitalium en el seno del diagnóstico de ITS detectadas a partir de muestras clínicas en un hospital terciario.

Métodos: Se procesaron 8.473 muestras de endocérvix, uretra, vagina, recto y otros, aplicando Allpex STI Essential Assay. Se revisaron más de 190 historias clínicas para determinar la patogenicidad de M. genitalium.

Resultados: Se detectó M. genitalium en 2,8% de casos. Hubo coinfecciones en 20% de los pacientes.

Conclusiones: M. genitalium a pesar de la baja incidencia en nuestra revisión, actualmente es un patógeno de valor en alza gracias al desarrollo de técnicas moleculares como PCR-multiplex. A partir de nuestra experiencia y las recomendaciones institucionales, tanto las técnicas de detección de ácidos nucleicos (NAATs) como los cultivos para gonococo deberían implementarse y coexistir para adecuar los tratamientos.

Keywords: Mycoplasma genitalium; coinfection; sexually transmitted infections.

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Conflict of interest statement

The authors declare no conflict of interest

References

    1. Taylor-Robinson D, Jensen JS. Mycoplasma genitalium: from Chrysalis to multicolored butterfly. Clin Microbiol Rev 2011; 24 (3):498-514. doi: 10.1128/CMR.00006-11. - DOI - PMC - PubMed
    1. Stary A. The Changing Spectrum of Sexually Transmitted Infections in Europe. Acta Derm Venereol 2020; 100: 242-247. doi: 10.2340/00015555-3470 - DOI - PMC - PubMed
    1. Mohammed H, Blomquist P, Ogaz D. et al. . 100 years of STIs in the UK: a review of national surveillance data. Sex Transm Infect 2018; 94(8):553-558. doi: 10.1136/sextrans-2017-053273. - DOI - PubMed
    1. Workowski KA, Berman S. Sexually transmitted diseases treatment guidelines, 2010. MMWR Recomm Rep. 2010; 59(RR-12):1-110. - PubMed
    1. Salmerón P, Viñado B, Arando Met al. . Neisseria gonorrhoeae antimicrobial resistance in Spain: a prospective multicentre study. J Antimicrob Chemother 2021;doi:10.1093/jac/dkab037. - DOI - PubMed