Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2021 Dec 5;9(12):e05183.
doi: 10.1002/ccr3.5183. eCollection 2021 Dec.

Pyelonephritis-associated Staphylococcus saprophyticus bacteremia in an immunocompetent host: Case report and review of the literature

Ahmad Matarneh  1 , Gawahir A Ali  2 , Wael Goravey  2
Affiliations
Case Reports

Pyelonephritis-associated Staphylococcus saprophyticus bacteremia in an immunocompetent host: Case report and review of the literature

Ahmad Matarneh et al. Clin Case Rep. .

Abstract

Staphylococcus saprophyticus is one of the coagulase-negative staphylococcus species. It is the second most frequent causative microorganism in acute uncomplicated urinary tract infections in young women. However, it is potentially capable of causing more invasive infections including bacteremia, particularly secondary to pyelonephritis. We present a young, previously healthy lady who presented with urinary symptoms and hemodynamic instability and was found to have multiple renal and ureteric calculi with pyelonephritis. Later, blood and urine cultures isolated methicillin-resistant S. saprophyticus. The patient was successfully treated with a course of antibiotics targeting the organism with a favorable outcome. The clinical presentations and management of this rare entity of S. saprophyticus bacteremia-related pyelonephritis are outlined. In addition, the literature on similar cases was reviewed to raise awareness and avoid devastating consequences.

Keywords: Staphylococcus saprophyticus; bacteremia; kidney calculi; pyelonephritis.

PubMed Disclaimer

Conflict of interest statement

The authors have no conflict of interest to declare.

Figures

FIGURE 1
FIGURE 1
CT KUB findings of (A) Hydronephrosis, (B) Renal calculi with evidence of hydronephrosis, (C) Ureteric calculi, and (D) Urinary bladder stone
See this image and copyright information in PMC

References

    1. Raz R, Colodner R, Kunin CM. Who are you ‐ Staphylococcus saprophyticus? Clin Infect Dis. 2005;40(6):896‐898. - PubMed
    1. Hovelius B, Mårdh PA. Staphylococcus saprophyticus as a common cause of urinary tract infections. Rev Infect Dis. 1984;6(3):328‐337. - PubMed
    1. Goldenring JM. Urinary tract infection with Staphylococcus saprophyticus . J Adolesc Heal Care. 1986;7(6):417‐418. - PubMed
    1. Choi SH, Woo JH, Jeong JY, et al. Clinical significance of Staphylococcus saprophyticus identified on blood culture in a tertiary care hospital. Diagn Microbiol Infect Dis. 2006;56(3):337‐339. - PubMed
    1. Wallmark G, Arremark I, Telander B. Staphylococcus saprophyticus: a frequent cause of acute urinary tract infection among female outpatients. J Infect Dis. 1978;138(6):791‐797. - PubMed

Publication types

LinkOut - more resources