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. 2021 Dec;42(6):839-858.
doi: 10.1055/s-0041-1740110. Epub 2021 Dec 16.

COVID-19 in Immunocompromised Patients: A Systematic Review

Anna Stainer  1   2 , Francesco Amati  1   2 , Giulia Suigo  2 , Edoardo Simonetta  3   4 , Andrea Gramegna  3   4 , Antonio Voza  1   5 , Stefano Aliberti  1   2
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COVID-19 in Immunocompromised Patients: A Systematic Review

Anna Stainer et al. Semin Respir Crit Care Med. 2021 Dec.

Abstract

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) was first identified as a novel coronavirus in Wuhan, Hubei province, central China, in December 2019, and is responsible for the 2019-to-present pandemic. According to the most recent data released by the World Health Organization, more than 200 million people have been infected by SARS-CoV-2 so far, and more than 4 million people died worldwide. Although our knowledge on SARS-CoV-2 and COVID-19 is constantly growing, data on COVID-19 in immunocompromised patients are still limited. The aim of the present systematic review is to describe clinical picture, disease severity, proposed treatment regimen, and response to vaccination in patients with different types and severity of immunosuppression.

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Conflict of interest statement

Disclosure The authors report no conflicts of interest in this work.

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