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Comment
. 2021 Dec 17;6(1):429.
doi: 10.1038/s41392-021-00850-7.

Greasy hair against obesity

Sandra Nickel  1 , Bruno Christ  2
Affiliations
Comment

Greasy hair against obesity

Sandra Nickel et al. Signal Transduct Target Ther. .
No abstract available

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Strategies to reduce adipose. Restriction of calorie intake and promotion of physical activity directly require individual initiative and action, while pharmacological interventions passively aim to decrease food uptake, e.g., via orexigenic (NPY, neuropeptide Y; AgRP, agouti-related peptide) or anorexigenic (CART, cocaine- and amphetamine-related transcript; pro-opiomelanocortin, POMC) neuropeptides. Beiging of white adipose tissue by, e.g., cold stress addresses fat depot breakdown via thermogenesis. TSLP activation of sebum production “sucks” off lipids from adipose tissue, but in addition impacts on skin barrier homeostatic functions
See this image and copyright information in PMC

Comment on

  • Thymic stromal lymphopoietin induces adipose loss through sebum hypersecretion.
    Choa R, Tohyama J, Wada S, Meng H, Hu J, Okumura M, May RM, Robertson TF, Pai RL, Nace A, Hopkins C, Jacobsen EA, Haldar M, FitzGerald GA, Behrens EM, Minn AJ, Seale P, Cotsarelis G, Kim B, Seykora JT, Li M, Arany Z, Kambayashi T. Choa R, et al. Science. 2021 Jul 30;373(6554):eabd2893. doi: 10.1126/science.abd2893. Science. 2021. PMID: 34326208 Free PMC article.

References

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