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. 2022 Mar;62(3):E17-E18.
doi: 10.1111/trf.16773. Epub 2021 Dec 18.

A novel RHD (c.509T>G, p.Met170Arg) allele shows weakened D expression

Mengyuan Ding  1 , Qin Li  2 , Hui Zhang  1 , Mingyuan Wang  1
Affiliations

A novel RHD (c.509T>G, p.Met170Arg) allele shows weakened D expression

Mengyuan Ding et al. Transfusion. 2022 Mar.
No abstract available

Keywords: blood group genomics; immunohematology (RBC serology, blood groups).

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References

REFERENCES

    1. Sandler SG, Chen LN, Flegel WA. Serological weak D phenotypes: a review and guidance for interpreting the RhD blood type using the RHD genotype. Br J Haematol. 2017;179:10-9.
    1. Trucco Boggione C, Nogués N, González-Santesteban C, Mufarrege N, Luján Brajovich M, Mattaloni SM, et al. Characterization of RHD locus polymorphism in D negative and D variant donors from Northwestern Argentina. Transfusion. 2019;59:3236-42.
    1. Qian C, Li Q, Yuan C, Bao Y, Yu S, Li S, et al. A new RhD variant allele is caused by a RhD 26 T > G mutation in a Chinese Han woman with a weak D phenotype. Transfusion. 2019;59:1400-1.
    1. Flegel WA, Zabern IV, Doescher A, Wagner FF, Avent NDJT. D variants at the RhD vestibule in the weak D type 4 and Eurasian D clusters. Transfusion. 2010;49:1059-69.

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