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Editorial
. 2022 Jan;15(1):e009290.
doi: 10.1161/CIRCHEARTFAILURE.121.009290. Epub 2021 Dec 20.

Targeting Inflammation in Pulmonary Artery Hypertension: Is It Time to Forget About the Lungs?

Douglas L Mann  1
Affiliations
Editorial

Targeting Inflammation in Pulmonary Artery Hypertension: Is It Time to Forget About the Lungs?

Douglas L Mann. Circ Heart Fail. 2022 Jan.
No abstract available

Keywords: Editorials; cytokines; inflammation; pulmonary artery.

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References

    1. Maron BA and Galiè N. Diagnosis, Treatment, and Clinical Management of Pulmonary Arterial Hypertension in the Contemporary Era: A Review. JAMA Cardiology. 2016;1:1056–1065. - PMC - PubMed
    1. Rabinovitch M, Guignabert C, Humbert M and Nicolls MR. Inflammation and immunity in the pathogenesis of pulmonary arterial hypertension. Circulation research. 2014;115:165–175. - PMC - PubMed
    1. Simpson CE, Chen JY, Damico RL, Hassoun PM, Martin LJ, Yang J, Nies M, Griffiths M, Vaidya RD, Brandal S, Pauciulo MW, Lutz KA, Coleman AW, Austin ED, Ivy DD, Nichols WC and Everett AD. Cellular sources of interleukin-6 and associations with clinical phenotypes and outcomes in pulmonary arterial hypertension. The European respiratory journal. 2020;55:1901761. - PMC - PubMed
    1. Prisco Sasha, Hartweck Lynn, Rose Lauren, Lima Patricia, Thenappan Thenappan, Archer Stephen, Prins Kurt. Inflammatory Glycoprotein 130 Signaling Links Changes in Microtubules and Junctophilin-2 to Altered Mitochondrial Metabolism and Right Ventricular Contractility. Circ Heart Fail. 2021. DOI: 10.1161/CIRCHEARTFAILURE.121.008574 - DOI - PMC - PubMed
    1. Xu S, Grande F, Garofalo A and Neamati N. Discovery of a novel orally active small-molecule gp130 inhibitor for the treatment of ovarian cancer. Molecular cancer therapeutics. 2013;12:937–49. - PubMed