[Gastric mucosal calcinosis]

Abstract

The gastric mucosal calcinosis is a benign condition corresponding to calcium deposits in the gastric mucosa. A 39-year-old women, with an history of transplantation, transplant rejection and hemodialysis, treated with corticosteroids and calcium/phosphoremic supplements, had chronic diarrhea. Gastroduodenal fibroscopy found an atypical atrophic gastritis appearance with small focal whitish deposits in the gastric mucosa. Histological examination revealed brown and gray-bluish crystalline deposits in superficial chorion, stained by Von Kossa, leading to a diagnosis of gastric mucosal calcinosis. This lesion can be categorized as systemic, dystrophic, iatrogenic and idiopathic. In our observation, gastric mucosal calcinosis was probably mixed, linked to renal disorders, and mainly to exogenous phosphocalcic drug intakes. The gastric mucosal calcinosis is commonly found in kidney transplant patients reaching a frequency of 15 to 29%.

Keywords: Calcinose de la muqueuse gastrique; Calcinose gastrique; Calcinose métabolique; Chronic kidney disease; Gastric mucosal calcinosis; Hypercalcemia; Hypercalcémie; Hyperphosphatemia; Hyperphosphatémie; Insuffisance rénale chronique; Metastatic calcinosis cutis; Metastatic gastric calcinosis.