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Review
. 2021 Dec 2:12:737743.
doi: 10.3389/fneur.2021.737743. eCollection 2021.

Endocrine Disorder in Patients With Craniopharyngioma

Zihao Zhou  1 , Sheng Zhang  2 , Fangqi Hu  3
Affiliations
Review

Endocrine Disorder in Patients With Craniopharyngioma

Zihao Zhou et al. Front Neurol. .

Abstract

Craniopharyngioma is an intracranial congenital epithelial tumor growing along the pathway of the embryonic craniopharyngeal tube. The main clinical symptoms of patients with craniopharyngioma include high intracranial pressure, visual field defect, endocrine dysfunction, and hypothalamic dysfunction. At present, the preferred treatment remains the surgical treatment, but the recovery of endocrine and hypothalamic function following surgery is limited. In addition, endocrine disorders often emerge following surgery, which seriously reduces the quality of life of patients after operation. So far, research on craniopharyngioma focuses on ways to ameliorate endocrine dysfunction. This article reviews the latest research progress on pathogenesis, manifestation, significance, and treatment of endocrine disorders in patients with craniopharyngioma.

Keywords: craniopharyngioma; endocrine disorders; pituitary hormone deficiency; risk; treatment.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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