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Case Reports
. 2021 Dec 17:2021:6841393.
doi: 10.1155/2021/6841393. eCollection 2021.

Trichosporon asahii Urinary Tract Infection in a Patient with Severe COVID-19

Verschoyle Cronyn  1 , John Howard  2 , Leslie Chiang  1 , Lisa Le  1 , Zandraetta Tims-Cook  1 , Alida M Gertz  1
Affiliations
Case Reports

Trichosporon asahii Urinary Tract Infection in a Patient with Severe COVID-19

Verschoyle Cronyn et al. Case Rep Infect Dis. .

Abstract

Trichosporon asahii is a yeast-like basidiomycete that is an emerging opportunistic infection in immunocompromised patients. Urinary tract infections due to T. asahii are rarely reported in the literature and typically seen only in immunocompromised patients. In addition to being immunocompromised, critically ill COVID-19 patients often have prolonged exposure to antibiotics, corticosteroids, and Foley catheters, which further increases their susceptibility to infection with T. asahii. There are limited case reports documenting successful treatment of T. asahii among hospitalized patients, particularly among COVID-19 patients, in the literature. Therefore, it is important that successful treatment regimens be reported. Here, we report a case of T. asahii urinary tract infection successfully treated with fluconazole and voriconazole in a 73-year-old male recovering from COVID-19. Urinary tract infections with T. asahii should be considered in persistently febrile COVID-19 patients with fungal urinary tract infections since prompt recognition and treatment can reduce the risk of disseminated disease and early mortality.

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Conflict of interest statement

None of the authors of this case report has any conflicts of interest to declare.

Figures

Figure 1
Figure 1
Flow chart outlining the timeline of events surrounding T. asahii infection, treatment, and resolution.
See this image and copyright information in PMC

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