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. 2021 Dec 20;16(1):727.
doi: 10.1186/s13018-021-02874-9.

All-cause mortality risk in aged femoral intertrochanteric fracture patients

Xin-Ping Li  1 , Ping Zhang  1 , Shi-Wen Zhu  2 , Ming-Hui Yang  3 , Xin-Bao Wu  2 , Xie-Yuan Jiang  2
Affiliations

All-cause mortality risk in aged femoral intertrochanteric fracture patients

Xin-Ping Li et al. J Orthop Surg Res. .

Abstract

Introduction: The 1-year mortality rate after femoral intertrochanteric fracture is higher than that of femoral neck fracture, which also belongs to hip fracture (Cui et al. in Arch Osteoporos 14(1):55, 2019). With the application of the concept of co-management model of orthopedics and geriatrics, the short-term and long-term mortality of all types of hip fractures has decreased (Van Heghe et al. in Calcif Tissue Int, 2021, https://doi.org/10.1007/s00223-021-00913-5 ). However, the mortality of Chinese femoral intertrochanteric fracture patients under this model has not been reported in the literatures.

Aim: This paper aims to study the risk factors of postoperative all-cause mortality in aged patients with femoral intertrochanteric fracture under the co-management model of orthopedics and geriatrics.

Materials and methods: This is a single-center prospective cohort study based on the real world, under the co-management of orthopedics and geriatrics, 363 patients aged ≥ 65 years with femoral intertrochanteric fracture were enrolled and followed up for 2-3 years; 52 patients were lost to follow up. Age, gender, body mass index (BMI), history of comorbidities, hip Bone Mineral Density (BMD), fracture history, 25(OH)D level, hemoglobin level, anti-osteoporosis treatment were risk factors to be tested. Kaplan-Meier survival curves and multivariate Cox proportional hazards models were constructed to analyze the impact of factors on all-cause mortality.

Results: (1) Most of the dead patients were older (the mean age was 83.4 years, compared with 79.8 years for surviving patients), with more complications and without anti-osteoporosis medication; gender, pre-fracture history, BMI, total hip BMD, hemoglobin, 25(OH)D had no difference between the dead and the living patients. (2) Elderly patients with Intertrochanteric fracture can benefit from the early treatment of Zoledronic Acid (within 3 days after the operation).

Conclusion: Under the co-management of orthopedics and geriatrics, to Chinese patients with Femoral Intertrochanteric fracture, Doctors should pay more attention to their age and chronic disease, and give anti-osteoporosis treatment if allowed.

Keywords: Femoral intertrochanteric fracture; Mortality; Osteoporosis; Zoledronic acid.

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Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
Cumulative survival of Intertrochanteric fracture patients by gender (A), age (B), Charlson comorbidity index (C) and dosing zoledronic acid or not (D)
See this image and copyright information in PMC

References

    1. Cui Z, Feng H, Meng X, Zhuang S, Liu Z, Ye K, et al. Age-specific 1-year mortality rates after hip fracture based on the populations in mainland China between the years 2000 and 2018: a systematic analysis. Arch Osteoporos. 2019;14(1):55. - PMC - PubMed
    1. Van Heghe A, Mordant G, Dupont J, Dejaeger M, Laurent MR, Gielen E. Effects of orthogeriatric care models on outcomes of hip fracture patients: a systematic review and meta-analysis. Calcif Tissue Int. 2021 doi: 10.1007/s00223-021-00913-5. - DOI - PMC - PubMed
    1. Si L, Winzenberg TM, Jiang Q, Chen M, Palmer AJ. Projection of osteoporosis-related fractures and costs in China: 2010–2050. Osteoporos Int. 2015;26(7):1929–1937. - PubMed
    1. Biz C, Fantoni I, Crepaldi N, Zonta F, Buffon L, Corradin M, et al. Clinical practice and nursing management of pre-operative skin or skeletal traction for hip fractures in elderly patients: a cross-sectional three-institution study. Int J Orthop Trauma Nurs. 2019;32:32–40. - PubMed
    1. Gibson-Smith D, Klop C, Elders P, Welsing P, Schoor N, Leufkens H, et al. The risk of major and any (nonhip) fragility fracture after hip fracture in the United Kingdom: 2000–2010. Osteoporos Int. 2014;25:2555–2563. - PubMed