Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Dec 20;9(1):77.
doi: 10.1186/s40560-021-00590-4.

Ultrafiltration in Japanese critically ill patients with acute kidney injury on renal replacement therapy

Koichi Kitamura  1 , Koichi Hayashi  2 , Shigeki Fujitani  2 , Raghavan Murugan  3   4 , Toshihiko Suzuki  5
Affiliations

Ultrafiltration in Japanese critically ill patients with acute kidney injury on renal replacement therapy

Koichi Kitamura et al. J Intensive Care. .

Abstract

A recent worldwide survey indicates an international diversity in net ultrafiltration (UFNET) practices for the treatment of fluid overload in critically ill patients with acute kidney injury (AKI) requiring renal replacement therapy (RRT). The sub-analysis of the survey has demonstrated that maximum doses of furosemide used before determination of diuretic resistance are lower in Japan than those prescribed worldwide and UFNET is lower but is initiated earlier. In contrast, the interval during which practitioners evaluate fluid balance is longer. The characterization of RRT in critically ill patients in Japan should unveil more appropriate approaches to the successful treatment of AKI.

Keywords: Diuretics; Fluid overload; Net ultrafiltration; Renal replacement therapy.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
Maximum doses of furosemide prescribed by survey practitioners. Statistical analyses were performed using the Chi-square test or Fisher’s exact test, as appropriate. Evaluation between two cohort groups (world vs. Japan) was conducted using a two-proportion z test
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Murugan R, Ostermann M, Peng Z, Kitamura K, Fujitani S, Romagnoli S, Di Lullo L, Srisawat N, Todi S, Ramakrishnan N, Hoste E, Puttarajappa CM, Bagshaw SM, Weisbord S, Palevsky PM, Kellum JA, Bellomo R, Ronco C. Net ultrafiltration prescription and practice among critically ill patients receiving renal replacement therapy: a multinational survey of critical care practitioners. Crit Care Med. 2020;48(2):e87–e97. doi: 10.1097/CCM.0000000000004092. - DOI - PubMed
    1. Lumlertgul N, Murugan R, Seylanova N, McCready P, Ostermann M. Net ultrafiltration prescription survey in Europe. BMC Nephrol. 2020;21:522. doi: 10.1186/s12882-020-02184-y. - DOI - PMC - PubMed
    1. Tanaka TD, Sawano M, Friedman M, Kohsaka S. Acute heart failure management in the USA and Japan: overview of practice patterns and review of evidence. ESC Heart Fail. 2018;5:932–948. doi: 10.1002/ehf2.12305. - DOI - PMC - PubMed
    1. Hasselblad V, Stough WG, Shah MR, Lokhnygina Y, O’Conner CM, Califf RM, Adams KF., Jr Relation between dose of loop diuretics and outcomes in a heart failure population: results of the ESCAPE trial. Eur J Heart Fail. 2007;9:1064–1069. doi: 10.1016/j.ejheart.2007.07.011. - DOI - PMC - PubMed
    1. Ho KM, Sheridan DJ. Meta-analysis of furosemide to prevent or treat acute renal failure. BMJ. 2006;333:420–425. doi: 10.1136/bmj.38902.605347.7C. - DOI - PMC - PubMed