"The pill" suppresses adolescent bone growth, no matter the estrogen dose

doi:10.1503/cmaj.80396

Comment

. 2021 Dec 20;193(50):E1922.

doi: 10.1503/cmaj.80396.

"The pill" suppresses adolescent bone growth, no matter the estrogen dose

Tatjana S Brajic¹, Azita Goshtasebi², Tamara B L Goldberg³, Abbey B Berenson⁴, Jerilynn C Prior⁵

Affiliations

¹ Physician, University of British Columbia, Vancouver, BC.
² Family physician, University of British Columbia, Vancouver, BC.
³ Professor, São Paulo State University, São Paulo, Brazil.
⁴ Professor, University of Texas Medical Branch, Galveston, Texas.
⁵ Professor, University of British Columbia, Vancouver, BC.

PMID: 34930769
PMCID: PMC8687508
DOI: 10.1503/cmaj.80396

Comment

"The pill" suppresses adolescent bone growth, no matter the estrogen dose

Tatjana S Brajic et al. CMAJ. 2021.

. 2021 Dec 20;193(50):E1922.

doi: 10.1503/cmaj.80396.

Authors

Tatjana S Brajic¹, Azita Goshtasebi², Tamara B L Goldberg³, Abbey B Berenson⁴, Jerilynn C Prior⁵

Affiliations

¹ Physician, University of British Columbia, Vancouver, BC.
² Family physician, University of British Columbia, Vancouver, BC.
³ Professor, São Paulo State University, São Paulo, Brazil.
⁴ Professor, University of Texas Medical Branch, Galveston, Texas.
⁵ Professor, University of British Columbia, Vancouver, BC.

PMID: 34930769
PMCID: PMC8687508
DOI: 10.1503/cmaj.80396

No abstract available

PubMed Disclaimer

Conflict of interest statement

Competing interests: None declared.

Comment on

Adolescent contraception.
Rosenthal MA, McQuillan SK. Rosenthal MA, et al. CMAJ. 2021 Aug 9;193(31):E1218. doi: 10.1503/cmaj.202413. CMAJ. 2021. PMID: 34373270 Free PMC article. No abstract available.

References

1. Rosenthal MA, McQuillan SK. Adolescent contraception. CMAJ 2021;193:E1218. - PMC - PubMed
1. Gersten J, Hsieh J, Weiss H, et al. . Effect of extended 30 μg ethinyl estradiol with continuous low-dose ethinyl estradiol and cyclic 20 μg ethinyl estradiol oral contraception on adolescent bone density: a randomized trial. J Pediatr Adolesc Gynecol 2016;29:635–42. - PubMed
1. Brajic TS, Berger C, Schlammerl K, et al. . Combined hormonal contraceptives use and bone mineral density changes in adolescent and young women in a prospective population-based Canada-wide observational study. J Musculoskelet Neuronal Interact 2018;18:227. - PMC - PubMed
1. Ott SM, Scholes D, LaCroix AZ, et al. . Effect of contraceptive use on bone biochemical markers in young women. J Clin Endocrinol Metab 2001;86:179–85. - PubMed
1. Goshtasebi A, Brajic TS, Scholes D, et al. . Adolescent use of combined hormonal contraception and peak bone mineral density accrual: a meta-analysis of international prospective controlled studies. Clin Endocrinol (Oxf) 2019;90:517. - PMC - PubMed

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[1] Rosenthal MA, McQuillan SK. Adolescent contraception. CMAJ 2021;193:E1218. - PMC - PubMed

[2] Rosenthal MA, McQuillan SK. Adolescent contraception. CMAJ 2021;193:E1218. - PMC - PubMed

[3] Gersten J, Hsieh J, Weiss H, et al. . Effect of extended 30 μg ethinyl estradiol with continuous low-dose ethinyl estradiol and cyclic 20 μg ethinyl estradiol oral contraception on adolescent bone density: a randomized trial. J Pediatr Adolesc Gynecol 2016;29:635–42. - PubMed

[4] Gersten J, Hsieh J, Weiss H, et al. . Effect of extended 30 μg ethinyl estradiol with continuous low-dose ethinyl estradiol and cyclic 20 μg ethinyl estradiol oral contraception on adolescent bone density: a randomized trial. J Pediatr Adolesc Gynecol 2016;29:635–42. - PubMed

[5] Brajic TS, Berger C, Schlammerl K, et al. . Combined hormonal contraceptives use and bone mineral density changes in adolescent and young women in a prospective population-based Canada-wide observational study. J Musculoskelet Neuronal Interact 2018;18:227. - PMC - PubMed

[6] Brajic TS, Berger C, Schlammerl K, et al. . Combined hormonal contraceptives use and bone mineral density changes in adolescent and young women in a prospective population-based Canada-wide observational study. J Musculoskelet Neuronal Interact 2018;18:227. - PMC - PubMed

[7] Ott SM, Scholes D, LaCroix AZ, et al. . Effect of contraceptive use on bone biochemical markers in young women. J Clin Endocrinol Metab 2001;86:179–85. - PubMed

[8] Ott SM, Scholes D, LaCroix AZ, et al. . Effect of contraceptive use on bone biochemical markers in young women. J Clin Endocrinol Metab 2001;86:179–85. - PubMed

[9] Goshtasebi A, Brajic TS, Scholes D, et al. . Adolescent use of combined hormonal contraception and peak bone mineral density accrual: a meta-analysis of international prospective controlled studies. Clin Endocrinol (Oxf) 2019;90:517. - PMC - PubMed

[10] Goshtasebi A, Brajic TS, Scholes D, et al. . Adolescent use of combined hormonal contraception and peak bone mineral density accrual: a meta-analysis of international prospective controlled studies. Clin Endocrinol (Oxf) 2019;90:517. - PMC - PubMed

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"The pill" suppresses adolescent bone growth, no matter the estrogen dose

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"The pill" suppresses adolescent bone growth, no matter the estrogen dose

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