Harnessing bacterial toxins to treat pain

Affiliations

¹ Neural Injury Group, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK.
² Neural Injury Group, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK. david.bennett@ndcn.ox.ac.uk.

Comment

Jimena Perez-Sanchez et al. Nat Neurosci. 2022 Feb.

. 2022 Feb;25(2):132-134.

doi: 10.1038/s41593-021-00981-8.

¹ Neural Injury Group, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK.
² Neural Injury Group, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK. david.bennett@ndcn.ox.ac.uk.

No abstract available

Comment on

Anthrax toxins regulate pain signaling and can deliver molecular cargoes into ANTXR2⁺ DRG sensory neurons.
Yang NJ, Isensee J, Neel DV, Quadros AU, Zhang HB, Lauzadis J, Liu SM, Shiers S, Belu A, Palan S, Marlin S, Maignel J, Kennedy-Curran A, Tong VS, Moayeri M, Röderer P, Nitzsche A, Lu M, Pentelute BL, Brüstle O, Tripathi V, Foster KA, Price TJ, Collier RJ, Leppla SH, Puopolo M, Bean BP, Cunha TM, Hucho T, Chiu IM. Yang NJ, et al. Nat Neurosci. 2022 Feb;25(2):168-179. doi: 10.1038/s41593-021-00973-8. Epub 2021 Dec 20. Nat Neurosci. 2022. PMID: 34931070 Free PMC article.

1. Dahlhamer, J. et al. MMWR Morb. Mortal. Wkly Rep. 67, 1001–1006 (2018). - DOI
1. Breivik, H., Collett, B., Ventafridda, V., Cohen, R. & Gallacher, D. Eur. J. Pain 10, 287–333 (2006). - DOI
1. Woolf, C. J. Biol. Psychiatry 87, 74–81 (2020). - DOI
1. Yang, N. J. et al. Nat. Neurosci. https://doi.org/10.1038/s41593-021-00973-8 (2021).
1. Yang, N. J. & Chiu, I. M. J. Mol. Biol. 429, 587–605 (2017). - DOI