Quadruple combination of quarter doses of blood pressure-lowering agents: a string QUARTET in the symphony of hypertension management?

Affiliations

¹ Cardiology Department, Sapienza University of Rome, Sant'Andrea Hospital, Via di Grottarossa 1035-1039, Rome 00189, Italy.
² Department of Pharmacology, Catholic University School of Medicine, Largo Francesco Vito 1, Rome 00168, Italy.

Comment

Massimo Volpe et al. Eur Heart J. 2021.

. 2021 Dec 21;42(48):4885-4886.

doi: 10.1093/eurheartj/ehab733.

¹ Cardiology Department, Sapienza University of Rome, Sant'Andrea Hospital, Via di Grottarossa 1035-1039, Rome 00189, Italy.
² Department of Pharmacology, Catholic University School of Medicine, Largo Francesco Vito 1, Rome 00168, Italy.

No abstract available

Comment on

Initial treatment with a single pill containing quadruple combination of quarter doses of blood pressure medicines versus standard dose monotherapy in patients with hypertension (QUARTET): a phase 3, randomised, double-blind, active-controlled trial.
Chow CK, Atkins ER, Hillis GS, Nelson MR, Reid CM, Schlaich MP, Hay P, Rogers K, Billot L, Burke M, Chalmers J, Neal B, Patel A, Usherwood T, Webster R, Rodgers A; QUARTET Investigators. Chow CK, et al. Lancet. 2021 Sep 18;398(10305):1043-1052. doi: 10.1016/S0140-6736(21)01922-X. Epub 2021 Aug 29. Lancet. 2021. PMID: 34469767 Clinical Trial.