Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Feb 16;60(2):e0247921.
doi: 10.1128/jcm.02479-21. Epub 2021 Dec 22.

Assessment of the Analytical Sensitivity of 10 Lateral Flow Devices against the SARS-CoV-2 Omicron Variant

Joshua Deerain  1 , Julian Druce  1 , Thomas Tran  1 , Mitchell Batty  1 , Yano Yoga  1 , Michael Fennell  2 , Dominic E Dwyer  2 , Jen Kok #  2 , Deborah A Williamson #  1   3
Affiliations

Assessment of the Analytical Sensitivity of 10 Lateral Flow Devices against the SARS-CoV-2 Omicron Variant

Joshua Deerain et al. J Clin Microbiol. .
No abstract available

Keywords: COVID-19; Omicron; antigen tests; diagnostics; infectious disease.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Figures

FIG 1
FIG 1
Analytical sensitivities of lateral flow devices against SARS-CoV-2 Delta and Omicron variants. Ten lateral flow devices were tested against 10-fold dilutions (1:100 to 1:100,000) of SARS-CoV-2 Delta and Omicron variants in quadruplicate. Green boxes indicate where SARS-CoV-2 antigen was detected for a single replicate, and orange boxes indicate where a negative result was observed. Mean Ct values from three replicates for each dilution were calculated using in-house RT-PCR for the N gene. The registered test names and manufacturers of the lateral flow devices included were as follows: (1) PanBio COVID-19 Ag rapid test device (nasal), Abbott Rapid Diagnostics Jena GmbH (Germany); (2) NowCheck COVID-19 antigen test, BioNote Inc. (Republic of Korea); (3) Roche SARS-CoV-2 rapid antigen test, SD Biosensor Inc. (Republic of Korea); (4) Standard Q COVID-19 Ag test, SD Biosensor Inc. (Republic of Korea); (5) SureScreen Diagnostics COVID-19 antigen rapid test cassette, BTNX Inc. (Canada); (6) VivaDiag SARS-CoV-2 Ag rapid test, VivaChek Biotech (Hangzhou) Co. Ltd. (China); (7) Wantai SARS-CoV-2 Ag rapid test (colloidal gold), Beijing Wantai Biological Pharmacy Enterprise Co. Ltd. (China); (8) Testsea SARS-CoV-2 antigen test kit, Hangzhou Testsea Biotechnology Co. Ltd. (China); (9) InnoScreen COVID-19 antigen rapid test device, Innovation Scientific Pty. Ltd. (Australia); and (10) LYHER novel coronavirus (COVID-19) antigen test kit (colloidal gold), Hangzhou Laihe Biotech Co. Ltd. (China).
See this image and copyright information in PMC

References

    1. Mina MJ, Peto TE, García-Fiñana M, Semple MG, Buchan IE. 2021. Clarifying the evidence on SARS-CoV-2 antigen rapid tests in public health responses to COVID-19. Lancet 397:1425–1427. 10.1016/S0140-6736(21)00425-6. - DOI - PMC - PubMed
    1. Therapeutic Goods Administration (TGA). 2021. COVID-19 rapid antigen self-tests that are approved in Australia. TGA, Woden, Australia. https://www.tga.gov.au/covid-19-rapid-antigen-self-tests-are-approved-au.... Accessed 15 December 2021.
    1. Caly L, Druce J, Roberts J, Bond K, Tran T, Kostecki R, Yoga Y, Naughton W, Taiaroa G, Seemann T, Schultz MB, Howden BP, Korman TM, Lewin SR, Williamson DA, Catton MG. 2020. Isolation and rapid sharing of the 2019 novel coronavirus (SARS-CoV-2) from the first patient diagnosed with COVID-19 in Australia. Med J Aust 212:459–462. 10.5694/mja2.50569. - DOI - PMC - PubMed
    1. Corman VM, Haage VC, Bleicker T, Schmidt ML, Mühlemann B, Zuchowski M, Jo WK, Tscheak P, Möncke-Buchner E, Müller MA, Krumbholz A, Drexler JF, Drosten C. 2021. Comparison of seven commercial SARS-CoV-2 rapid point-of-care antigen tests: a single-centre laboratory evaluation study. Lancet Microbe 2:e311–e319. 10.1016/S2666-5247(21)00056-2. - DOI - PMC - PubMed
    1. Bekliz M, Adea K, Essaidi-Laziosi M, Sacks JA, Escadafal C, Kaiser L, Eckerle I. 24 November 2021. SARS-CoV-2 antigen-detecting rapid tests for the delta variant. Lancet Microbe 10.1016/S2666-5247(21)00302-5. - DOI - PMC - PubMed

Publication types

Supplementary concepts