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Review
. 2021 Dec;33(8):775-783.
doi: 10.1016/j.sdentj.2021.08.008. Epub 2021 Aug 28.

Effect of silicon dioxide nanoparticles on the flexural strength of heat-polymerized acrylic denture base material: A systematic review and meta-analysis

Ahmad M Al-Thobity  1 , Mohammed M Gad  1
Affiliations
Review

Effect of silicon dioxide nanoparticles on the flexural strength of heat-polymerized acrylic denture base material: A systematic review and meta-analysis

Ahmad M Al-Thobity et al. Saudi Dent J. 2021 Dec.

Abstract

Objective: This study evaluated the influence of silicon dioxide (SiO2) nanoparticles on the flexural strength of heat-polymerized denture base materials.

Background: Nanoparticles have been incorporated into the denture base materials in different proportions to enhance the mechanical properties. Recently, the incorporation of SiO2 nanoparticles at low concentrations has shown promising outcomes.

Materials and methods: Following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) protocol, this study was designed with the following focused question: "Does the addition of SiO2 nanoparticles improve the flexural strength of heat-polymerized acrylic resins?" The inclusion criteria included in-vitro studies that assessed the flexural strength of SiO2 nanoparticle-reinforced heat-polymerized acrylic denture base resins tested according to American Dental Association specifications. The database search involved articles published from 2005 to 2020 on PubMed/MEDLINE, Web of Science, Google Scholar, and Scopus using the following keywords: SiO2, nanosilica, silica oxide, nanoparticles, denture base resin, acrylic resin, polymethyl methacrylate, PMMA, flexural strength, and mechanical properties.

Results: Among 167 studies, five papers fulfilled the inclusion criteria and were added for the data analysis and meta-analysis. Proportions of incorporated SiO2 nanoparticles ranged from 0.25% to 15% and the reported flexural strength values for the reinforced acrylic resin ranged from 41.25 MPa to 124.56 MPa. The meta-analysis revealed no significant effect on the flexural strength between the unmodified and the SiO2 nanoparticle-reinforced acrylic resin.

Conclusion: Therefore, No particular concentration of SiO2 nanoparticles could be recommended for heat-polymerized denture base reinforcement.

Keywords: Denture base; Flexural strength; Meta-analysis; PMMA; SiO2 nanoparticles; Systematic review.

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Figures

Fig.1
Fig.1
Flow chart of the search strategy and study selection following PRISMA protocol.
Fig.2
Fig.2
Forest plot for 1% SiO2 reinforcement.
Fig.3
Fig.3
Forest plot for 3% SiO2 reinforcement.
Fig.4
Fig.4
Forest plot for 5% SiO2 reinforcement.
Fig.5
Fig.5
Forest plot for 7% SiO2 reinforcement.
See this image and copyright information in PMC

References

    1. Al-Harbi F.A., Abdel-Halim M.S., Gad M.M., Fouda S.M., Baba N.Z., AlRumaih H.S., Akhtar S. Effect of Nanodiamond Addition on Flexural Strength, Impact Strength, and Surface Roughness of PMMA Denture Base. J. Prosthodont. 2019;28(1):e417–e425. doi: 10.1111/jopr.12969. - DOI - PubMed
    1. Al-Thobity A.M. The Impact of Polymerization Technique and Glass-Fiber Reinforcement on the Flexural Properties of Denture Base Resin Material. Eur. J. Dent. 2020;14(01):092–099. doi: 10.1055/s-0040-1701922. - DOI - PMC - PubMed
    1. Alnamel H.A., Mudhaffer M. The Effect of Silicon Di Oxide Nano - Fillers Reinforcement on Some Properties of Heat Cure Polymethyl Methacrylate Denture Base Material. J. Baghdad Coll. Dent. 2014;26:32–36. doi: 10.12816/0015142. - DOI
    1. Arima T., Murata H., Hamada T. Properties of highly cross-linked autopolymerizing reline acrylic resins. J. Prosthet. Dent. 1995;73(1):55–59. doi: 10.1016/S0022-3913(05)80273-2. - DOI - PubMed
    1. Ashton, H., 2009. The Incorporation of Nanomaterials into Polymer Media, in: Polymer Nanocomposites Handbook. CRC Press. https://doi.org/10.1201/9781420009804-c3.

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