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Review
. 2022 Jan;16(1):7.
doi: 10.3892/br.2021.1490. Epub 2021 Nov 26.

Mechanisms of gram-positive vancomycin resistance (Review)

Samy Selim  1
Affiliations
Review

Mechanisms of gram-positive vancomycin resistance (Review)

Samy Selim. Biomed Rep. 2022 Jan.

Abstract

Vancomycin-resistant bacteria (VRB) are important consideration in medicine and public health as they can cause life-threatening infections that appear to be resistant to therapy and persist in the body after medication. A wide spectrum of antimicrobial resistance characteristics, as well as various environmental and animal settings underlie the evolution of the most prevalent the most prevalent van genes in the VRB genome, indicating significant gene flow. As illnesses caused by VRB have become increasingly complex, several previously effective therapeutic techniques have become ineffective, complicating clinical care further. The focus of this review is the mechanism of vancomycin resistance in Enterococci, Staphylococci and Lactobacilli.

Keywords: gram-positive bacteria; mechanisms; resistance; vancomycin.

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Conflict of interest statement

The author has declared that no competing interest exists.

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