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Review
. 2021 Dec 18;8(12):1200.
doi: 10.3390/children8121200.

Pediatric Cardio-Oncology Medicine: A New Approach in Cardiovascular Care

Affiliations
Review

Pediatric Cardio-Oncology Medicine: A New Approach in Cardiovascular Care

Hugo R Martinez et al. Children (Basel). .

Abstract

Survival for pediatric patients diagnosed with cancer has improved significantly. This achievement has been made possible due to new treatment modalities and the incorporation of a systematic multidisciplinary approach for supportive care. Understanding the distinctive cardiovascular characteristics of children undergoing cancer therapies has set the underpinnings to provide comprehensive care before, during, and after the management of cancer. Nonetheless, we acknowledge the challenge to understand the rapid expansion of oncology disciplines. The limited guidelines in pediatric cardio-oncology have motivated us to develop risk-stratification systems to institute surveillance and therapeutic support for this patient population. Here, we describe a collaborative approach to provide wide-ranging cardiovascular care to children and young adults with oncology diseases. Promoting collaboration in pediatric cardio-oncology medicine will ultimately provide excellent quality of care for future generations of patients.

Keywords: cardiovascular healthcare; early detection; individualization of therapies; oncology therapies; pediatric cardiology-oncology; predictive healthcare models.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Stakeholders caring for pediatric cardio-oncology patients. Created with BioRender.com.
Figure 2
Figure 2
Conceptual model of a continuum of cardiovascular care for children undergoing oncology therapies. Created with BioRender.com.
Figure 3
Figure 3
Underlying causes of heart failure in PedCO. Created with BioRender.com.
Figure 4
Figure 4
Geographical representation of the LBCH/SJCRH Pediatric Cardio-Oncology webinar series.

References

    1. Howlader N., Noone A.M., Krapcho M., Miller D., Brest A., Yu M., Ruhl J., Tatalovich Z., Mariotto A., Lewis D.R., et al. SEER Cancer Statistics Review (CSR), 1975–2017. National Cancer Institute; Bethesda, MD, USA: 2020. [(accessed on 8 September 2021)]. Available online: https://seer.cancer.gov/csr/1975_2017/
    1. Campia U., Moslehi J.J., Amiri-Kordestani L., Barac A., Beckman J.A., Chism D.D., Cohen P., Groarke J.D., Herrmann J., Reilly C.M., et al. Cardio-Oncology: Vascular and Metabolic Perspectives: A Scientific Statement from the American Heart Association. Circulation. 2019;139:e579–e602. doi: 10.1161/CIR.0000000000000641. - DOI - PMC - PubMed
    1. Lipshultz S.E., Adams M.J., Colan S.D., Constine L.S., Herman E.H., Hsu D.T., Hudson M.M., Kremer L.C., Landy D.C., Miller T.L., et al. Long-term cardiovascular toxicity in children, adolescents, and young adults who receive cancer therapy: Pathophysiology, course, monitoring, management, prevention, and research directions: A scientific statement from the American Heart Association. Circulation. 2013;128:1927–1995. doi: 10.1161/CIR.0b013e3182a88099. - DOI - PubMed
    1. Carver J.R., Szalda D., Ky B. Asymptomatic cardiac toxicity in long-term cancer survivors: Defining the population and recommendations for surveillance. Semin. Oncol. 2013;40:229–238. doi: 10.1053/j.seminoncol.2013.01.005. - DOI - PMC - PubMed
    1. Cardinale D., Colombo A., Bacchiani G., Tedeschi I., Meroni C.A., Veglia F., Civelli M., Lamantia G., Colombo N., Curigliano G., et al. Early detection of anthracycline cardiotoxicity and improvement with heart failure therapy [A study that validates the concept that early detection and intervention on anthracycline toxicity improves outcomes] Circulation. 2015;131:1981–1988. doi: 10.1161/CIRCULATIONAHA.114.013777. - DOI - PubMed

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