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Comment
. 2022 Oct;47(11):1873-1874.
doi: 10.1038/s41386-021-01253-6. Epub 2021 Dec 23.

Neuromedin U: a neuropeptide modulator of GABA transmission contributes to cocaine seeking

Annie Ly  1 , David H Root  2
Affiliations
Comment

Neuromedin U: a neuropeptide modulator of GABA transmission contributes to cocaine seeking

Annie Ly et al. Neuropsychopharmacology. 2022 Oct.
No abstract available

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1. Proposed GABAergic pathway regulated by neuromedin and play a role in cocaine self-administration.
Rats were trained on fixed ratio (FR) schedules of cocaine self-administration before advancing to a progressive ratio schedule. Viral knockdown of the NMU receptor by short hairpin RNA (shNMUR2) from afferent projections of the nucleus accumbens shell increased lever presses for cocaine infusions under the progressive ratio (PR) reinforcement schedule.
See this image and copyright information in PMC

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