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Review
. 2021 Nov;46(21):5522-5532.
doi: 10.19540/j.cnki.cjcmm.20210520.201.

[Research progress on chemical constituents and pharmacological activities of seabuckthorn and prediction of its Q-markers]

[Article in Chinese]
Ning-Ning Wang  1 , Wen-Hui Zheng  2 , Kai-Xue Zhang  1 , Xiu-Feng Wen  3 , Shun-Guang Lu  3 , Zhi-Gang Yang  1
Affiliations
Review

[Research progress on chemical constituents and pharmacological activities of seabuckthorn and prediction of its Q-markers]

[Article in Chinese]
Ning-Ning Wang et al. Zhongguo Zhong Yao Za Zhi. 2021 Nov.

Abstract

Seabuckthorn contains flavonoids, tannins, terpenoids, polysaccharides, and vitamins, which have anti-inflammation,anti-oxidation, liver protection, anti-cardiovascular disease, anti-aging, immune enhancing, anti-tumor, and anti-bacterial activities.We reviewed the papers focusing on the chemical constituents, pharmacological activities, and utilization of seabuckthorn. The quality markers(Q-markers) of seabuckthorn were predicted and analyzed based on original plant phylogeny, chemical composition correlation, traditional medicinal properties, pharmacodynamic correlation, traditional and extended efficacy, pharmacokinetics, metabolic processes, and measurable components. With this review, we aim to provide theoretical reference for the quality control and quality standard establishment of seabuckthorn, so as to promote the rational exploitation and utilization of seabuckthorn resources, and improve the healthy and sustainable development of seabuckthorn industry.

Keywords: chemical constituent; development and utilization; pharmacological activity; quality marker(Q-marker); seabuckthorn.

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