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. 2022 Mar;102(3):115613.
doi: 10.1016/j.diagmicrobio.2021.115613. Epub 2021 Nov 29.

Comparison of the QuantiFERON-TB® Gold Plus on LIAISON® XL and T-SPOT.TB for the diagnosis of latent Mycobacterium tuberculosis infection in a low tuberculosis incidence population

Laura Heireman  1 , Peggy Bruynseels  2 , Kim Camps  2 , Dieter Geysels  2 , Evelyne Huyghe  2 , Emmanuel André  3 , Natasja Van Gasse  3
Affiliations

Comparison of the QuantiFERON-TB® Gold Plus on LIAISON® XL and T-SPOT.TB for the diagnosis of latent Mycobacterium tuberculosis infection in a low tuberculosis incidence population

Laura Heireman et al. Diagn Microbiol Infect Dis. 2022 Mar.

Abstract

The current study compared the QuantiFERON-TB® Gold Plus on LIAISON® XL to the T-SPOT.TB for the diagnosis of latent Mycobacterium tuberculosis infection on 125 patient samples. A high agreement of qualitative results (90%) was observed between both methods with 3% major discrepancies, half of which were false negative results with the T-SPOT.TB.

Keywords: Interferon-gamma release assay; Liaison® XL; Mycobacterium tuberculosis; QuantiFERON-TB Gold Plus; T-SPOT.TB.

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