CoV-Spectrum: analysis of globally shared SARS-CoV-2 data to identify and characterize new variants
- PMID: 34954792
- PMCID: PMC8896605
- DOI: 10.1093/bioinformatics/btab856
CoV-Spectrum: analysis of globally shared SARS-CoV-2 data to identify and characterize new variants
Abstract
Summary: The CoV-Spectrum website supports the identification of new SARS-CoV-2 variants of concern and the tracking of known variants. Its flexible amino acid and nucleotide mutation search allows querying of variants before they are designated by a lineage nomenclature system. The platform brings together SARS-CoV-2 data from different sources and applies analyses. Results include the proportion of different variants over time, their demographic and geographic distributions, common mutations, hospitalization and mortality probabilities, estimates for transmission fitness advantage and insights obtained from wastewater samples.
Availability and implementation: CoV-Spectrum is available at https://cov-spectrum.org. The code is released under the GPL-3.0 license at https://github.com/cevo-public/cov-spectrum-website.
© The Author(s) 2021. Published by Oxford University Press.
References
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- Aksamentov I. et al. (2021) Nextclade: clade assignment, mutation calling and quality control for viral genomes. J. Open Source Softw., 6, 3773.
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- Chen C., Stadler T. (2021) Lightweight API for Sequences (LAPIS). https://github.com/cevo-public/LAPIS (25 November 2021, date last accessed).
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