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Review
. 2022 Feb 1;30(1):3-12.
doi: 10.1097/MOO.0000000000000780.

The role of nasopharyngectomy in the management of nasopharyngeal carcinoma

Wei-Hsin Wang  1   2 , Chien-Fu Yeh  2   3 , Ming-Ying Lan  2   3
Affiliations
Review

The role of nasopharyngectomy in the management of nasopharyngeal carcinoma

Wei-Hsin Wang et al. Curr Opin Otolaryngol Head Neck Surg. .

Abstract

Purpose of review: Recently, endoscopic nasopharyngectomy (ENPG) has become an effective treatment for locally recurrent nasopharyngeal carcinoma (NPC). This article reviews recent publications on ENPG and specifically addresses the surgical anatomy of the nasopharynx and discusses several important issues regarding ENPG.

Recent findings: The surgical techniques for ENPG have been previously described in several studies. The latest published data revealed good outcomes of ENPG compared with intensity-modulated radiation therapy (IMRT) in recurrent NPC. In addition, ENPG avoids severe reirradiation side effects. This review highlights the surgical anatomy of ENPG, which is important in preventing possible serious complications.

Summary: ENPG is a good option for managing recurrent NPC. Careful preoperative evaluation and a full understanding of the surgical anatomy help in preventing damage to nearby critical neurovascular structure. Long-term follow-up is still needed to evaluate its eventual morbidity and efficacy.

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References

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    1. Wang EW, Zanation AM, Gardner PA, et al. ICAR: endoscopic skull-base surgery. Int Forum Allergy Rhinol 2019; 9:S145–s365.

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