Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2021 Dec 2;9(12):1426.
doi: 10.3390/vaccines9121426.

Current Take on Systemic Sclerosis Patients' Vaccination Recommendations

Giuseppe Murdaca  1 , Giovanni Noberasco  2 , Dario Olobardi  2 , Claudio Lunardi  3 , Matteo Maule  3 , Lorenzo Delfino  3 , Massimo Triggiani  4 , Chiara Cardamone  4 , Devis Benfaremo  5   6 , Gianluca Moroncini  5   6 , Angelo Vacca  7 , Nicola Susca  7 , Sebastiano Gangemi  8 , Paola Quattrocchi  8 , Laura Sticchi  2   9 , Giancarlo Icardi  2   9 , Andrea Orsi  2   9
Affiliations
Review

Current Take on Systemic Sclerosis Patients' Vaccination Recommendations

Giuseppe Murdaca et al. Vaccines (Basel). .

Abstract

Systemic sclerosis (SSc) is a rare autoimmune inflammatory rheumatic disease. The prevalence of SSc ranges from 7 to 700 cases per million worldwide. Due to multiple organ involvement and constant inflammatory state, this group of patients presents an increased risk of infectious diseases. This paper aimed to gather the up-to-date evidence on vaccination strategies for patients with SSc and to be a useful tool for the prevention and management of infectious diseases. The authors conducted a scoping review in which each paragraph presents data on a specific vaccine's safety, immunogenicity, and efficacy. The work deals with the following topics: SARS-CoV-2, seasonal influenza, S. pneumoniae, HAV, HBV, HZV, N. meningitidis, H. influenzae, HPV, and diphtheria-tetanus-pertussis.

Keywords: H. influenzae; HPV; HZV; N. meningitidis; S. pneumoniae; SARS-CoV-2; diphtheria-tetanus-pertussis; hepatitis; influenza; systemic sclerosis.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

References

    1. Elhai M., Avouac J., Walker U., Matucci-Cerinic M., Riemekasten G., Airò P., Hachulla E., Valentini G., Carreira P., Cozzi F., et al. A gender gap in primary and secondary heart dysfunctions in systemic sclerosis: A EUSTAR prospective study. Ann. Rheum. Dis. 2016;75:163–169. doi: 10.1136/annrheumdis-2014-206386. - DOI - PubMed
    1. Khedoe P., Marges E., Hiemstra P., Ninaber M., Geelhoed M. Interstitial Lung Disease in Patients with Systemic Sclerosis: Toward Personalized-Medicine-Based Prediction and Drug Screening Models of Systemic Sclerosis-Related Interstitial Lung Disease (SSc-ILD) Front. Immunol. 2020;11:19090. doi: 10.3389/fimmu.2020.01990. - DOI - PMC - PubMed
    1. Alba M.A., Velasco C., Simeón C.P., Fonollosa V., Trapiella L., Egurbide M.V., Sáez L., Castillo M.J., Callejas J.L., Camps M.T., et al. Early- versus Late-Onset Systemic Sclerosis. Medicine. 2014;93:73–81. doi: 10.1097/MD.0000000000000018. - DOI - PMC - PubMed
    1. Nagaraja V., Matucci-Cerinic M., Furst D.E., Kuwana M., Allanore Y., Denton C.P., Raghu G., McLaughlin V., Rao P.S., Seibold J.R., et al. Current and Future Outlook on Disease Modification and Defining Low Disease Activity in Systemic Sclerosis. Arthritis Rheumatol. 2020;72:1049–1058. doi: 10.1002/art.41246. - DOI - PMC - PubMed
    1. Barahona-Correa J.E., De la Hoz A., López M.J., Garzón J., Allanore Y., Quintana-López G. Infections and systemic sclerosis: An emerging challenge. Rev. Colomb. Reumatol. 2020;27:62–84. doi: 10.1016/j.rcreue.2019.12.004. - DOI

LinkOut - more resources