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Review

Diabetes Mellitus in Patients with Cancer

In: Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000.
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Review

Diabetes Mellitus in Patients with Cancer

Nalinie Joharatnam-Hogan et al.
Free Books & Documents

Excerpt

There is increasing evidence of an association between cancer and diabetes mellitus. People with Type 2 diabetes are at increased risk of malignancy due to shared risk factors between the two conditions, and people with a diagnosis of cancer may develop new onset diabetes or impaired glycemic control, partly as a result of the systemic anti-cancer treatments (SACT) they receive. Many newer targeted anti-cancer treatments can have off-target metabolic toxicities not seen with conventional chemotherapy agents. Early recognition of diabetes or hyperglycemia in people with cancer can improve outcomes. This chapter aims to summarize these associations, provide an overview of how different SACT modalities can impact glycemic control, and highlight key recommendations for the management of this complex patient group. For complete coverage of all related areas of Endocrinology, please visit our on-line FREE web-text, WWW.ENDOTEXT.ORG.

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References

    1. International Diabetes Federation. IDF Diabetes Atlas 2025. Available at https://diabetesatlas.org/atlas/tenth-edition/. Accessed June 2025.
    1. American Diabetes Association. Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes-2021. Diabetes Care [Internet]. 2021; 44(Supplement 1): S15-S33. 10.2337/dc21-S002 - DOI - PubMed
    1. Diagnosis and classification of diabetes mellitus. Diabetes Care. 2010;33 Suppl 1(Suppl 1):S62-9. doi: 10.2337/dc10-S062 - DOI - PMC - PubMed
    1. Pearson-Stuttard J, Papadimitriou N, Markozannes G, et al. Type 2 Diabetes and Cancer: An Umbrella Review of Observational and Mendelian Randomization Studies. Cancer Epidemiol Biomarkers Prev. 2021. Jun;30(6):1218-1228. doi: . 10.1158/1055-9965 - DOI - PMC - PubMed
    1. Giovannucci E, Harlan DM, Archer MC, et al. Diabetes and cancer: a consensus report. CA Cancer J Clin. 2010;60(4):207-21. doi: 10.3322/caac.20078 - DOI - PubMed

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