Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2022 Mar 1;44(2):31-39.
doi: 10.1097/MPH.0000000000002384.

Infantile Hemangioma: A Current Review

Affiliations
Review

Infantile Hemangioma: A Current Review

Kristy S Pahl et al. J Pediatr Hematol Oncol. .

Abstract

Infantile hemangiomas (IHs) are common vascular lesions which are benign but can cause significant functional and cosmetic morbidity. Since the fortuitous discovery of propranolol being effective to treat IH over a decade ago, the therapy and prognosis for children with IH have improved dramatically. Oral propranolol (as well as other oral beta-blockers and topical timolol) are safe and effective treatments, and have now supplanted other therapies. Making the correct diagnosis is crucial, because other vascular lesions can mimic IH. In addition, IH can be the first manifestation of an underlying syndrome. For IH requiring treatment, initiating treatment early is key to optimizing success. Therefore, early recognition and referral, if necessary, are important. Continued research on IH, both basic science and clinical, should result in continued advances.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

References

    1. Kilcline C, Frieden IJ. Infantile hemangiomas: how common are they? A systematic review of the medical literature. Pediatr Dermatol. 2008;25:168–173.
    1. Munden A, Butschek R, Tom WL, et al. Prospective study of infantile haemangiomas: incidence, clinical characteristics and association with placental anomalies. Br J Dermatol. 2014;170:907–913.
    1. ISSVA. Classification of Vascular Anomalies 2018 International Society for the Study of Vascular Anomalies. Available at: issva.org/classification . Accessed October 5, 2021.
    1. Liberale C, Rozell-Shannon L, Moneghini L, et al. Stop calling me cavernous hemangioma! A literature review on misdiagnosed bony vascular anomalies. J Invest Surg. 2020. [Epub ahead of print].
    1. Pahl KS, Kim K, Sams C, et al. Inconsistency in classifying vascular anomalies: what’s in a name? Pediatr Blood Cancer. 2018. doi: 10.1002/pbc.26836. - DOI