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Observational Study
. 2022 Apr;36(4):e14572.
doi: 10.1111/ctr.14572. Epub 2022 Jan 10.

Hospitalization and death after recovery from acute COVID-19 among renal transplant recipients

Nikolina Basic-Jukic  1 , Sanjin Racki  2 , Ivana Tolj  3 , Mirna Aleckovic  4 , Batric Babovic  5 , Ivana Juric  1 , Vesna Furic-Cunko  1 , Lea Katalinic  1 , Dubravka Mihaljevic  3 , Sofija Vujic  2 , Enisa Mesic  4 , Bojan Jelakovic  1 , Zeljko Kastelan  6
Affiliations
Observational Study

Hospitalization and death after recovery from acute COVID-19 among renal transplant recipients

Nikolina Basic-Jukic et al. Clin Transplant. 2022 Apr.

Abstract

Introduction: Data on post-COVID-19 in renal transplant recipients (RTR) is scarce. We investigated the rate of hospitalizations, reasons for hospital admission, and mortality rate among RTR who survived acute COVID-19.

Methods: A multi-center retrospective observational cohort study measured hospital admission and death to 180 days after acute SARS-CoV-2 infection in 308 adult patients.

Results: The median age was 57 years, 64.9% were male. All patients had at least one comorbidity, and 26.3% had diabetes. Data on post-COVID-19 course was available for 267 patients, and 49 of them (15.9%) required hospital treatment after recovery from the acute infection. The most common indications included pneumonia (24.5%) and renal allograft dysfunction (22.4%), 7 (14.3%) had sepsis and 5 (10.2%) had thrombotic events. A median duration of the hospital stay was 12 days. Six patients (2.2%) died due to multiorgan failure, respiratory insufficiency or urosepsis. The strongest predictor for hospitalization after acute COVID-19 was hospitalization for acute SARS-CoV-2 infection, while better allograft function decreased the probability of hospitalization.

Conclusion: Delayed consequences of acute COVID-19 are highly prevalent and the health care systems should be prepared to respond to the needs of RTR suffering from post-COVID-19 complications.

Keywords: COVID-19; hospitalization; outcome; post-COVID-19; rehospitalization; renal transplantations.

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References

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